ENSDARG00000007136


Danio rerio

Features
Gene ID: ENSDARG00000007136
  
Biological name :gtf2h4
  
Synonyms : general transcription factor IIH, polypeptide 4 / gtf2h4 / sh3bp5lb
  
Possible biological names infered from orthology : Q7L8J4 / Q99LH9 / SH3 binding domain protein 5 like / SH3BP5L
  
Species: Danio rerio
  
Chr. number: 19
Strand: -1
Band:
Gene start: 27283072
Gene end: 27336092
  
Corresponding Affymetrix probe sets: Dr.14818.1.A1_at (Zebrafish Array)   Dr.188.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000113057
Ensembl peptide - ENSDARP00000144186
NCBI entrez gene - 558670     See in Manteia.
swissprot - F1R096
swissprot - Q1LWR3
ZFIN ID - ZDB-GENE-030131-6779
ZFIN ID - ZDB-GENE-060503-310
Ensembl - ENSDARG00000007136
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q7L8J4ENSG00000175137Homo sapiens
 Q99LH9ENSMUSG00000013646Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
sh3bp5la / SH3-binding domain protein 5-like, a / Q7L8J4* / Q99LH9* / SH3BP5L* / SH3 binding domain protein 5 like*ENSDARG0000001916049
sh3bp5a / SH3-domain binding protein 5a (BTK-associated)ENSDARG0000010052926
sh3bp5b / SH3-domain binding protein 5b (BTK-associated) / O60239* / SH3BP5* / SH3 domain binding protein 5*ENSDARG0000010397824


Protein motifs (from Interpro)
Interpro ID Name
 IPR004598  Transcription factor TFIIH subunit p52/Tfb2
 IPR007940  SH3-binding 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0061099 negative regulation of protein tyrosine kinase activity IBA
 biological_processGO:0070816 phosphorylation of RNA polymerase II C-terminal domain IBA
 cellular_componentGO:0000439 core TFIIH complex IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005675 holo TFIIH complex IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0008353 RNA polymerase II carboxy-terminal domain kinase activity IBA
 molecular_functionGO:0017124 SH3 domain binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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