ENSDARG00000008141


Danio rerio
proteinrbl1transcriptiongsmadregulationcellcycleb-boxa-boxcyclin-likec-terminaln-terminalretinoblastomafamilyretinoblastoma-likernapolymeraseiinucleusfactorcomplexearlyheterotrimerregulatescyclindassociatedevents

Features
Gene ID: ENSDARG00000008141
  
Biological name :rbl1
  
Synonyms : rbl1 / retinoblastoma-like 1 (p107)
  
Possible biological names infered from orthology : P28749 / Q64701 / RB transcriptional corepressor like 1 / Retinoblastoma-like protein 1
  
Species: Danio rerio
  
Chr. number: 6
Strand: -1
Band:
Gene start: 51549203
Gene end: 51573975
  
Corresponding Affymetrix probe sets: Dr.6209.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000124719
Ensembl peptide - ENSDARP00000068355
NCBI entrez gene - 795522     See in Manteia.
RefSeq - NM_001130610
RefSeq Peptide - NP_001124082
swissprot - F8W2I3
swissprot - F1QY31
ZFIN ID - ZDB-GENE-030131-8179
Ensembl - ENSDARG00000008141
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RBL1ENSGALG00000001332Gallus gallus
 RBL1ENSG00000080839Homo sapiens
 Rbl1ENSMUSG00000027641Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rbl2 / retinoblastoma-like 2 (p130) / Q64700* / Q08999* / Retinoblastoma-like protein 2 * / RB transcriptional corepressor like 2*ENSDARG0000004563648
rb1 / retinoblastoma 1 / P13405* / P06400* / RB transcriptional corepressor 1* / Retinoblastoma-associated protein *ENSDARG0000000678221


Protein motifs (from Interpro)
Interpro ID Name
 IPR002719  Retinoblastoma-associated protein, B-box
 IPR002720  Retinoblastoma-associated protein, A-box
 IPR013763  Cyclin-like
 IPR015030  Retinoblastoma-associated protein, C-terminal
 IPR024599  Retinoblastoma-associated protein, N-terminal
 IPR028309  Retinoblastoma protein family
 IPR028310  Retinoblastoma-like protein 1


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclenitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclenitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclenitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclenitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclenitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclenitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclenitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclenitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclenitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell cyclenitrogen compound metabnitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processorganic substance metaborganic substance metabolic processcell cyclecell cycle
cellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellorganelleprotein-containing complexcellcellorganelleorganelleprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IEA


Pathways (from Reactome)
Pathway description
G0 and Early G1
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Cyclin D associated events in G1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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