ENSDARG00000008363


Danio rerio

Features
Gene ID: ENSDARG00000008363
  
Biological name :mcl1b
  
Synonyms : mcl1b / MCL1, BCL2 family apoptosis regulator b
  
Possible biological names infered from orthology : Induced myeloid leukemia cell differentiation / MCL1 / MCL1, BCL2 family apoptosis regulator / P97287 / Q07820
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 29586004
Gene end: 29587969
  
Corresponding Affymetrix probe sets: Dr.25133.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000124170
Ensembl peptide - ENSDARP00000124404
swissprot - A2BF68
swissprot - F8W4Q8
ZFIN ID - ZDB-GENE-030825-1
Ensembl - ENSDARG00000008363
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MCL1ENSGALG00000044383Gallus gallus
 MCL1ENSG00000143384Homo sapiens
 Mcl1ENSMUSG00000038612Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mcl1a / MCL1, BCL2 family apoptosis regulator a / MCL1* / Q07820* / P97287* / MCL1, BCL2 family apoptosis regulator* / Induced myeloid leukemia cell differentiation *ENSDARG0000000977939
bcl2l10 / BCL2 like 10ENSDARG0000002676615


Protein motifs (from Interpro)
Interpro ID Name
 IPR002475  Bcl2-like
 IPR013281  Apoptosis regulator, Mcl-1
 IPR026298  Blc2 family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007088 regulation of mitotic nuclear division IGI
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IBA
 biological_processGO:0042981 regulation of apoptotic process IGI
 biological_processGO:0043009 chordate embryonic development IGI
 biological_processGO:0043066 negative regulation of apoptotic process IGI
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0045839 negative regulation of mitotic nuclear division IGI
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IBA
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway IBA
 cellular_componentGO:0005741 mitochondrial outer membrane IBA
 molecular_functionGO:0042803 protein homodimerization activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism apoptotic process increased process quality , abnormal
whole organism cell proliferation increased process quality , abnormal
whole organism mitotic cell cycle process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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