ENSDARG00000009020


Danio rerio

Features
Gene ID: ENSDARG00000009020
  
Biological name :cnr1
  
Synonyms : cannabinoid receptor 1 / cnr1
  
Possible biological names infered from orthology : Mus musculus cannabinoid receptor 1 (brain) (Cnr1), transcript variant 2, mRNA. / P21554 / P47746
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 902412
Gene end: 915234
  
Corresponding Affymetrix probe sets: DrAffx.1.12.S1_at (Zebrafish Array)   NM_212820_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000007647
Ensembl peptide - ENSDARP00000134375
NCBI entrez gene - 404209     See in Manteia.
RefSeq - NM_212820
RefSeq Peptide - NP_997985
swissprot - Q7T3Q3
ZFIN ID - ZDB-GENE-040312-3
Ensembl - ENSDARG00000009020
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CNR1ENSGALG00000037511Gallus gallus
 CNR1ENSG00000118432Homo sapiens
 Cnr1ENSMUSG00000044288Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cnr2 / cannabinoid receptor 2 / P34972* / P47936*ENSDARG0000003997031
s1pr5a / sphingosine-1-phosphate receptor 5aENSDARG0000004052620
s1pr2 / Q9I8K8 / sphingosine-1-phosphate receptor 2 / O95136*ENSDARG0000003654819
s1pr3a / sphingosine-1-phosphate receptor 3a / S1PR3* / Q9Z0U9* / Q99500* / sphingosine-1-phosphate receptor 3*ENSDARG0000004247019
s1pr4 / sphingosine-1-phosphate receptor 4 / O95977* / Q9Z0L1*ENSDARG0000007485119
lpar2b / lysophosphatidic acid receptor 2b / LPAR2* / Q9HBW0* / lysophosphatidic acid receptor 2*ENSDARG0000004256118
s1pr1 / sphingosine-1-phosphate receptor 1 / O08530* / P21453*ENSDARG0000004269018
s1pr5b / sphingosine-1-phosphate receptor 5b / S1PR5* / Q9H228* / Q91X56* / sphingosine-1-phosphate receptor 5*ENSDARG0000005219218
lpar2a / lysophosphatidic acid receptor 2a / LPAR2* / Q9HBW0* / lysophosphatidic acid receptor 2*ENSDARG0000004233817
gpr12 / G protein-coupled receptor 12 / P35412* / P47775*ENSDARG0000006293417
lpar3 / lysophosphatidic acid receptor 3 / Q9UBY5*ENSDARG0000010181417
gpr185b / G protein-coupled receptor 185 bENSDARG0000003656016
gpr6 / G protein-coupled receptor 6 / P46095*ENSDARG0000005240016
gpr186 / G protein-coupled receptor 186ENSDARG0000009486016
gpr185a / G protein-coupled receptor 185 aENSDARG0000006040015
lpar1 / lysophosphatidic acid receptor 1 / P61793* / Q92633*ENSDARG0000009984014


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000810  Cannabinoid receptor type 1
 IPR002230  Cannabinoid receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IMP
 biological_processGO:0006555 methionine metabolic process IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007409 axonogenesis IMP
 biological_processGO:0007413 axonal fasciculation IMP
 biological_processGO:0008610 lipid biosynthetic process IMP
 biological_processGO:0038171 cannabinoid signaling pathway IEA
 biological_processGO:2000253 positive regulation of feeding behavior IMP
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004949 cannabinoid receptor activity IEA


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000036 liver and biliary system liver and biliary system spatial pattern , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
anatomical structure decreased amount , abnormal
Show

 ZFA:0000123 liver liver lipid increased amount , abnormal
liver cysteine decreased amount , abnormal
liver S-adenosyl-L-methionine decreased amount , abnormal
liver S-adenosyl-L-homocysteine decreased amount , abnormal
liver methionine decreased amount , abnormal
liver homocysteine decreased amount , abnormal
liver serine decreased amount , abnormal
liver homoserine decreased amount , abnormal
liver size , ameliorated
liver decreased size , abnormal
liver decreased distribution , abnormal
liver cell proliferation decreased rate , abnormal
Show

 ZFA:0000208 gall bladder gall bladder lipase activity absent , abnormal
Show

 ZFA:0000543 medial longitudinal fasciculus medial longitudinal fasciculus structure , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased amount , abnormal
Show

 ZFA:0001338 intestine intestine lipase activity decreased occurrence , abnormal
Show

 ZFA:0005165 common bile duct common bile duct morphology , abnormal
common bile duct decreased branchiness , abnormal
Show

 ZFA:0005857 bile bile accumulation liver , abnormal
Show

 ZFA:0009111 hepatocyte hepatocyte morphology , abnormal
hepatocyte morphology , ameliorated
hepatocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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