ENSDARG00000013307


Danio rerio
lrpl19ribosomalproteinedomainribosomesubunitsnonsensemediateddecaynmdexonjunctioncomplexejcnervoushindbrainconservedsiteeukaryotictranslationhemopoiesisintracellularcytosoliclargernabindingstructuralconstituent

Features
Gene ID: ENSDARG00000013307
  
Biological name :rpl19
  
Synonyms : Q6P5L3 / ribosomal protein L19 / rpl19
  
Possible biological names infered from orthology : P84098 / P84099
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 16229911
Gene end: 16232442
  
Corresponding Affymetrix probe sets: Dr.9746.3.S1_at (Zebrafish Array)   NM_213208_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000105649
NCBI entrez gene - 406489     See in Manteia.
RefSeq - NM_213208
RefSeq Peptide - NP_998373
swissprot - Q6P5L3
ZFIN ID - ZDB-GENE-040426-2290
Ensembl - ENSDARG00000013307
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RPL19ENSGALG00000001658Gallus gallus
 RPL19ENSG00000108298Homo sapiens
 Rpl19ENSMUSG00000017404Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000196  Ribosomal protein L19/L19e
 IPR015972  Ribosomal protein L19/L19e, domain 1
 IPR015973  Ribosomal protein L19/L19e, domain 2
 IPR015974  Ribosomal protein L19/L19e, domain 3
 IPR023638  Ribosomal protein L19/L19e conserved site
 IPR033935  Ribosomal protein L19, eukaryotic


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabolic processbiosynthetic processcellular metabolic processprimary metabolic processorganic substance metabolic processanatomical structure developmentnitrogen compound metabnitrogen compound metabolic processbiosynthetic processbiosynthetic processcellular metabolic proccellular metabolic processprimary metabolic proceprimary metabolic processorganic substance metaborganic substance metabolic processanatomical structure deanatomical structure development
organic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeorganic cyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomeorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound bindingstructural constituent of ribosomestructural constituent of ribosome
cellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellcellprotein-containing complexprotein-containing complexorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IBA
 biological_processGO:0030097 hemopoiesis IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0003735 structural constituent of ribosome IBA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
SRP-dependent cotranslational protein targeting to membrane
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
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 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000029 hindbrain hindbrain quality , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary quality , abnormal
midbrain hindbrain boundary condensed , abnormal
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 ZFA:0000084 yolk yolk circular , abnormal
yolk grey , abnormal
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 ZFA:0000106 extension extension decreased thickness , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle distended , abnormal
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 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
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 ZFA:0000142 peripheral nervous system peripheral nervous system nerve neoplastic , abnormal
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 ZFA:0001094 whole organism whole organism viability , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk decreased thickness , abnormal
trunk atrophied , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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