Manteia

ENSDARG00000013649

Danio rerio

Features

Gene ID:	ENSDARG00000013649

Biological name :	casr

Synonyms :	calcium-sensing receptor / casr

Possible biological names infered from orthology :	Extracellular calcium-sensing receptor / P41180 / Q9QY96

Species:	Danio rerio

Chr. number:	5
Strand:	-1
Band:
Gene start:	67768162
Gene end:	67783593

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000013946 NCBI entrez gene - 560607 See in Manteia. RefSeq - NM_001351665 RefSeq Peptide - NP_001338594 swissprot - F1R4B8 ZFIN ID - ZDB-GENE-050119-8 Ensembl - ENSDARG00000013649

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
CASR	ENSGALG00000038405	Gallus gallus
CASR	ENSG00000036828	Homo sapiens
Casr	ENSMUSG00000051980	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
si:dkey-47k20.3 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50* / Vmn2r53* / Vmn2r54...	ENSDARG00000029635	37
si:dkey-47k20.8 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50* / Vmn2r53* / Vmn2r54...	ENSDARG00000035214	37
v2rh32 / si:dkey-47k20.5 / vomeronasal 2 receptor, h32 / E9Q6I0* / Vmn2r14* / Gm14496* / Vmn2r10* / Vmn2r18* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / V...	ENSDARG00000040594	37
v2rx1 / vomeronasal 2 receptor, x1 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50* /...	ENSDARG00000040632	37
si:dkey-47k20.9 / si:dkey-47k20.4 / E9Q6I0* / Vmn2r14* / Gm14496* / Vmn2r10* / Vmn2r18* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50* / ...	ENSDARG00000055920	37
si:dkey-47k20.7 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50* / Vmn2r53* / Vmn2r54...	ENSDARG00000056014	37
v2rh10 / vomeronasal 2 receptor, h10 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50*...	ENSDARG00000061883	37
si:ch211-203b20.4 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50* / Vmn2r53* / Vmn2r...	ENSDARG00000091790	37
olfcs1 / olfactory receptor C family, s1 / E9Q6I0* / Vmn2r14* / Gm14496* / Vmn2r10* / Vmn2r18* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2...	ENSDARG00000104241	37
si:dkey-47k20.5 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50* / Vmn2r53* / Vmn2r54...	ENSDARG00000115763	37
v2rl1 / vomeronasal 2 receptor, l1 / Vmn2r2* / Vmn2r3* / Vmn2r4* / Vmn2r5* / Vmn2r6* / Vmn2r7* / Vmn2r1* / vomeronasal 2, receptor 2* / vomeronasal 2, receptor 3* / vomeronasal 2, receptor ...	ENSDARG00000005942	36
v2rh9 / si:dkey-47k20.3 / vomeronasal 2 receptor, h9 / E9Q6I0* / Vmn2r14* / Gm14496* / Vmn2r10* / Vmn2r18* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn...	ENSDARG00000056009	36
v2ra18 / vomeronasal 2 receptor, a18 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50*...	ENSDARG00000061903	36
si:ch211-229c8.13 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50* / Vmn2r53* / Vmn2r...	ENSDARG00000067828	36
v2rh14 / vomeronasal 2 receptor, h14 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50*...	ENSDARG00000068520	36
si:dkey-47k20.4 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50* / Vmn2r53* / Vmn2r54...	ENSDARG00000068549	36
olfcd3 / olfactory receptor C family, d3 / E9Q6I0* / Vmn2r14* / Gm14496* / Vmn2r10* / Vmn2r18* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2...	ENSDARG00000068576	36
v2rh13 / vomeronasal 2 receptor, h13 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50*...	ENSDARG00000088192	36
v2ra16 / vomeronasal 2 receptor, a16 / E9Q6I0* / Vmn2r18* / Gm14496* / Vmn2r10* / Vmn2r14* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2r50*...	ENSDARG00000091990	36
olfcg7 / olfactory receptor C family, g7 / E9Q6I0* / Vmn2r14* / Gm14496* / Vmn2r10* / Vmn2r18* / Vmn2r19* / Vmn2r20* / Vmn2r21* / Vmn2r24* / Vmn2r27* / Vmn2r31* / Vmn2r36* / Vmn2r44* / Vmn2...	ENSDARG00000098225	36

Protein motifs (from Interpro)

Interpro ID	Name
IPR000337	GPCR, family 3
IPR001828	Receptor, ligand binding region
IPR011500	GPCR, family 3, nine cysteines domain
IPR017978	GPCR family 3, C-terminal
IPR028082	Periplasmic binding protein-like I

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001501	skeletal system development	IMP
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0055074	calcium ion homeostasis	IMP
cellular_component	GO:0005886	plasma membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0004871	obsolete signal transducer activity	IEA
molecular_function	GO:0004930	G-protein coupled receptor activity	IEA

Pathways (from Reactome)

Pathway description

G alpha (q) signalling events

G alpha (i) signalling events

Class C/3 (Metabotropic glutamate/pheromone receptors)

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0000135	notochord	notochord morphology , abnormal	Show
ZFA:0000317	postcranial axial skeleton	postcranial axial skeleton skeletal system development behavioral quality of a process , abnormal	Show
ZFA:0001056	myotome	myotome morphology , abnormal	Show
ZFA:0001094	whole organism	whole organism axis decreased length , abnormal whole organism decreased amount , abnormal whole organism increased amount , abnormal	Show
ZFA:0001115	trunk	trunk increased curvature , abnormal	Show
ZFA:0005606	cranial vault	cranial vault dorso-ventrally flattened , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr