ENSDARG00000013776


Danio rerio

Features
Gene ID: ENSDARG00000013776
  
Biological name :thop1
  
Synonyms : thimet oligopeptidase 1 / thop1
  
Possible biological names infered from orthology : P52888
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 7183025
Gene end: 7212097
  
Corresponding Affymetrix probe sets: Dr.4044.1.A1_at (Zebrafish Array)   NM_001002355_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000129723
Ensembl peptide - ENSDARP00000046669
Ensembl peptide - ENSDARP00000109333
Ensembl peptide - ENSDARP00000128894
NCBI entrez gene - 436628     See in Manteia.
RefSeq - NM_001002355
RefSeq - XM_005172818
RefSeq Peptide - NP_001002355
swissprot - Q6DHR6
swissprot - X1WF90
swissprot - X1WHL0
swissprot - E7EZ90
ZFIN ID - ZDB-GENE-040718-47
Ensembl - ENSDARG00000013776
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 THOP1ENSGALG00000041934Gallus gallus
 THOP1ENSG00000172009Homo sapiens
 Thop1ENSMUSG00000004929Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nln / neurolysin (metallopeptidase M3 family) / Q9BYT8* / Q91YP2* / neurolysin* / Neurolysin, mitochondrial *ENSDARG0000001923360


Protein motifs (from Interpro)
Interpro ID Name
 IPR001567  Peptidase M3A/M3B catalytic domain
 IPR024080  Neurolysin/Thimet oligopeptidase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006518 peptide metabolic process IBA
 cellular_componentGO:0005758 mitochondrial intermembrane space IBA
 molecular_functionGO:0004222 metalloendopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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