ENSDARG00000014218
Danio rerio binding mecp2 methyl-cpg dna regulation transcription neuron ganglion dna-templated development dna-binding domain superfamily protein mecp rna polymerase ii neuromuscular junction locomotory behavior response radiation differentiation axon presynapse assembly heterochromatin nucleus cytosol
Features Gene ID: ENSDARG00000014218 Biological name :mecp2 Synonyms : mecp2 / methyl CpG binding protein 2 Possible biological names infered from orthology : P51608 / Q9Z2D6 Species: Danio rerio Chr. number: 8 Strand: -1 Band: Gene start: 7616573 Gene end: 7637640 Corresponding Affymetrix probe sets: Dr.20599.1.S1_at (Zebrafish Array) NM_212736_at (Zebrafish Genome Array with custom cdf files) Cross references: Ensembl peptide - ENSDARP00000109399 Ensembl peptide - ENSDARP00000040671 NCBI entrez gene - 335250
See in Manteia .
RefSeq - NM_212736 RefSeq - NM_001328555 RefSeq Peptide - NP_001315484 RefSeq Peptide - NP_997901 swissprot - A8WIP2 swissprot - Q7T2T7 ZFIN ID - ZDB-GENE-030131-7190 Ensembl - ENSDARG00000014218
See expression report in BioGPS See gene description in Wikigenes See co-cited genes in PubMed Ortholog prediction (from Ensembl )
Paralog prediction (from Ensembl ) mbd4 / methyl-CpG binding domain protein 4 / O95243* / methyl-CpG binding domain 4, DNA glycosylase* ENSDARG00000110298 3
Protein motifs (from Interpro )
Gene Ontology (GO ) nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cellular component organization locomotory behavior response to abiotic stimulus anatomical structure development cellular developmental process cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cellular component organization locomotory behavior response to abiotic stimulus anatomical structure development cellular developmental process cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cellular component organization locomotory behavior response to abiotic stimulus anatomical structure development cellular developmental process cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cellular component organization locomotory behavior response to abiotic stimulus anatomical structure development cellular developmental process cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cellular component organization locomotory behavior response to abiotic stimulus anatomical structure development cellular developmental process cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cellular component organization locomotory behavior response to abiotic stimulus anatomical structure development cellular developmental process cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cellular component organization locomotory behavior response to abiotic stimulus anatomical structure development cellular developmental process cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cellular component organization locomotory behavior response to abiotic stimulus anatomical structure development cellular developmental process cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cellular component organization locomotory behavior response to abiotic stimulus anatomical structure development cellular developmental process cellular component biogenesis nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process organic substance metabolic process cellular component organization locomotory behavior response to abiotic stimulus anatomical structure development cellular developmental process cellular component biogenesis nitrogen comnitrogen compound metabolic process biosyntheticbiosynthetic process cellular metcellular metabolic process primary metaprimary metabolic process organic subsorganic substance metabolic process cellular comcellular component organization locomotory blocomotory behavior response to response to abiotic stimulus anatomical sanatomical structure development cellular devcellular developmental process cellular comcellular component biogenesis organic cyclic compound binding heterocyclic compound binding small molecule binding organic cyclic compound binding heterocyclic compound binding small molecule binding organic cyclic compound binding heterocyclic compound binding small molecule binding organic cyclic compound binding heterocyclic compound binding small molecule binding organic cyclic compound binding heterocyclic compound binding small molecule binding organic cyclic compound binding heterocyclic compound binding small molecule binding organic cyclic compound binding heterocyclic compound binding small molecule binding organic cyclic compound binding heterocyclic compound binding small molecule binding organic cyclic compound binding heterocyclic compound binding small molecule binding organic cyclic compound binding heterocyclic compound binding small molecule binding organic cyclic compound bindingorganic cyclic compound binding heterocyclic compound bindingheterocyclic compound binding small molecule bindingsmall molecule binding cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cell organelle cellcell organelleorganelle
Pathways (from Reactome )No match
Phenotype (from MGI , Zfin or HPO ) ZFA:0000008 brain brain has fewer parts of type neuron , abnormal brain has extra parts of type neuronal stem cell , abnormal brain has extra parts of type astrocyte , abnormal brain Notch signaling pathway increased occurrence , abnormal brain neuron differentiation decreased occurrence , abnormal brain astrocyte differentiation increased occurrence , abnormal brain neural precursor cell proliferation increased occurrence , abnormal brain neuronal stem cell proliferative , abnormal
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ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal anatomical structure decreased amount , abnormal
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ZFA:0000295 trigeminal ganglion trigeminal ganglion has fewer parts of type motor neuron , abnormal trigeminal ganglion axon decreased length , abnormal trigeminal ganglion axon arborization disrupted , abnormal trigeminal ganglion axon branchiness , abnormal
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ZFA:0001056 myotome myotome neuromuscular junction increased distribution , abnormal myotome presynaptic density increased amount , abnormal
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ZFA:0001094 whole organism whole organism increased amount , abnormal whole organism decreased amount , abnormal
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ZFA:0001291 facial ganglion facial ganglion has fewer parts of type motor neuron , abnormal
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ZFA:0007067 vagal ganglion vagal ganglion has fewer parts of type motor neuron , abnormal
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ZFA:0009150 Rohon-Beard neuron Rohon-Beard neuron axon decreased length , abnormal Rohon-Beard neuron axon decreased branchiness , abnormal
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ZFA:0009243 CaP motoneuron CaP motoneuron axonogenesis disrupted , abnormal CaP motoneuron axon morphology , abnormal CaP motoneuron axon decreased branchiness , abnormal
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ZFA:0009247 secondary motor neuron secondary motor neuron axon morphology , abnormal secondary motor neuron axon decreased branchiness , abnormal
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Interacting proteins (from Reactome )No match
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