ENSDARG00000015059


Danio rerio

Features
Gene ID: ENSDARG00000015059
  
Biological name :daam1a
  
Synonyms : daam1a / dishevelled associated activator of morphogenesis 1a
  
Possible biological names infered from orthology : DAAM1 / Disheveled-associated activator of morphosis 1 / dishevelled associated activator of morphogenesis 1 / Q8BPM0 / Q9Y4D1
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 14467015
Gene end: 14591764
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000127933
Ensembl peptide - ENSDARP00000143770
Ensembl peptide - ENSDARP00000132829
Ensembl peptide - ENSDARP00000023227
NCBI entrez gene - 557451     See in Manteia.
RefSeq - XM_017351772
swissprot - E7F6Y9
swissprot - A0A0R4IER9
swissprot - X1WCJ0
ZFIN ID - ZDB-GENE-030911-6
Ensembl - ENSDARG00000015059
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DAAM1ENSGALG00000012017Gallus gallus
 DAAM1ENSG00000100592Homo sapiens
 Daam1ENSMUSG00000034574Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
daam1b / dishevelled associated activator of morphogenesis 1b / DAAM1* / Q8BPM0* / Q9Y4D1* / Disheveled-associated activator of morphosis 1 * / dishevelled associated activator of morphogenesis 1*ENSDARG0000000968982
daam2 / dishevelled associated activator of morphogenesis 2 / Q80U19* / Q86T65* / Disheveled-associated activator of morphosis 2 *ENSDARG0000002839365
diaph2 / diaphanous-related formin 2 / 2 * / O60879* / O70566*ENSDARG0000007606025
fmnl3 / Q6NXC0 / formin-like 3 / Q8IVF7* / Q6ZPF4* / Formin-like protein 3 *ENSDARG0000000437224
fmnl2a / formin-like 2a / FMNL2* / A2APV2* / Q96PY5* / formin like 2* / Formin-like protein 2 *ENSDARG0000001258624
fmnl1a / formin-like 1a / FMNL1* / O95466* / Q9JL26* / formin like 1* / Formin-like protein 1 *ENSDARG0000005571324
fmnl2b / formin-like 2b / FMNL2* / A2APV2* / Q96PY5* / formin like 2* / Formin-like protein 2 *ENSDARG0000007504124
diaph3 / diaphanous-related formin 3 / 3 * / Q9NSV4* / Q9Z207*ENSDARG0000009078524
fhdc3 / FH2 domain containing 3ENSDARG0000006912912
fhdc1 / FH2 domain containing 1 / Q3ULZ2* / Q9C0D6* / FH2 domain-containing protein 1 *ENSDARG0000007481212
fhdc4 / FH2 domain containing 4ENSDARG0000008626112
CABZ01055365.1 / FMNL1* / O95466* / formin like 1*ENSDARG0000010426311
fhdc2 / FH2 domain containing 2ENSDARG0000009976710
fhdc5 / FH2 domain containing 5 / FHDC1* / Q3ULZ2* / Q9C0D6* / FH2 domain containing 1* / FH2 domain-containing protein 1 *ENSDARG000000959629
CABZ01057928.1 / DIAPH1* / O60610* / diaphanous related formin 1*ENSDARG000001150828
CABZ01060373.1 / INF2* / Q27J81* / inverted formin, FH2 and WH2 domain containing*ENSDARG000001170695


Protein motifs (from Interpro)
Interpro ID Name
 IPR010472  Formin, FH3 domain
 IPR010473  Formin, GTPase-binding domain
 IPR011989  Armadillo-like helical
 IPR014767  Diaphanous autoregulatory (DAD) domain
 IPR014768  Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
 IPR015425  Formin, FH2 domain
 IPR016024  Armadillo-type fold
 IPR027650  Disheveled-associated activator of morphogenesis 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016043 cellular component organization IEA
 biological_processGO:0021986 habenula development IMP
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0048793 pronephros development IMP
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0017048 Rho GTPase binding IEA


Pathways (from Reactome)
Pathway description
PCP/CE pathway
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye fused with eye , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct branched , abnormal
pronephric duct undulate , abnormal
pronephric duct in contact with pronephric duct , abnormal
Show

 ZFA:0000151 pronephros pronephros morphology , abnormal
Show

 ZFA:0000197 dorsal habenular nucleus dorsal habenular nucleus neuron projection terminus incomplete structure , abnormal
dorsal habenular nucleus neuron morphology , abnormal
dorsal habenular nucleus neuron projection decreased amount , abnormal
Show

 ZFA:0000213 habenula habenula cytoskeleton organization decreased process quality , abnormal
habenula dendrite decreased volume , abnormal
habenula dendrite truncated , abnormal
habenula filamentous actin disorganized , abnormal
habenula determination of left/right asymmetry in diencephalon process quality , abnormal
Show

 ZFA:0000903 interpeduncular nucleus tegmentum interpeduncular nucleus tegmentum innervation process quality , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
post-vent region bent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr