ENSDARG00000015681


Danio rerio

Features
Gene ID: ENSDARG00000015681
  
Biological name :gsk3ab
  
Synonyms : glycogen synthase kinase 3 alpha b / gsk3ab
  
Possible biological names infered from orthology : AC006486.1 / glycogen synthase kinase 3 alpha / GSK3A / P49840 / Q2NL51
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 11242443
Gene end: 11292148
  
Corresponding Affymetrix probe sets: Dr.259.1.S1_at (Zebrafish Array)   NM_131390_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000114920
Ensembl peptide - ENSDARP00000011670
NCBI entrez gene - 30664     See in Manteia.
RefSeq - NM_131390
RefSeq Peptide - NP_571465
swissprot - E9QDL5
swissprot - Q9YH61
ZFIN ID - ZDB-GENE-990714-3
Ensembl - ENSDARG00000015681
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AC006486.1ENSG00000268643Homo sapiens
 GSK3AENSG00000105723Homo sapiens
 Gsk3aENSMUSG00000057177Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gsk3aa / glycogen synthase kinase 3 alpha a / GSK3A* / Q2NL51* / P49840* / AC006486.1* / glycogen synthase kinase 3 alpha*ENSDARG0000002950186
gsk3b / glycogen synthase kinase 3 beta / P49841* / Q9WV60*ENSDARG0000001780374
si:dkeyp-80c12.7 / GSK3B (1 of many) / GSK3B* / P49841* / Q9WV60* / glycogen synthase kinase 3 beta*ENSDARG0000005246873


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0009953 dorsal/ventral pattern formation IGI
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0055013 cardiac muscle cell development IMP
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart cardiac muscle cell apoptotic , abnormal
heart cardiac muscle cell decreased amount , abnormal
heart linear , abnormal
Show

 ZFA:0000149 primitive heart tube primitive heart tube linear , abnormal
Show

 ZFA:0001094 whole organism whole organism anterior-posterior axis deformed , abnormal
whole organism anterior-posterior axis apoptotic , abnormal
Show

 ZFA:0001114 head head degenerate , abnormal
head apoptotic , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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