ENSDARG00000015824


Danio rerio
nuclearmembranelemd3domainmaninnerrnarecognitionmotiflemorganizationenveloperegulationintegralcomponentbindinglem-likesuperfamily-srcp-c-terminalproteinangiogenesisnucleusbmpsignalingpathwaymeioticattachmenttelomereintracellularsignal

Features
Gene ID: ENSDARG00000015824
  
Biological name :lemd3
  
Synonyms : lemd3 / LEM domain containing 3
  
Possible biological names infered from orthology : Q9Y2U8
  
Species: Danio rerio
  
Chr. number: 4
Strand: -1
Band:
Gene start: 12917164
Gene end: 12930086
  
Corresponding Affymetrix probe sets: Dr.3312.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000005474
NCBI entrez gene - 558474     See in Manteia.
RefSeq - NM_001044864
RefSeq Peptide - NP_001038329
swissprot - Q5TZH9
ZFIN ID - ZDB-GENE-030131-490
Ensembl - ENSDARG00000015824
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LEMD3ENSGALG00000009873Gallus gallus
 LEMD3ENSG00000174106Homo sapiens
 Lemd3ENSMUSG00000048661Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000504  RNA recognition motif domain
 IPR003887  LEM domain
 IPR011015  LEM/LEM-like domain superfamily
 IPR018996  Man1-Src1p-C-terminal domain
 IPR034394  MAN1, RNA recognition motif
 IPR034997  Inner nuclear membrane protein Man1


Gene Ontology (GO)
anatomical structure developmentcellular component organizationnitrogen compound metabolic processcell communicationbiosynthetic processresponse to endogenous stimulusresponse to chemicalcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusestablishment of localizationcell cyclecellular localizationchromosome segregationanatomical structure developmentcellular component organizationnitrogen compound metabolic processcell communicationbiosynthetic processresponse to endogenous stimulusresponse to chemicalcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusestablishment of localizationcell cyclecellular localizationchromosome segregationanatomical structure developmentcellular component organizationnitrogen compound metabolic processcell communicationbiosynthetic processresponse to endogenous stimulusresponse to chemicalcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusestablishment of localizationcell cyclecellular localizationchromosome segregationanatomical structure developmentcellular component organizationnitrogen compound metabolic processcell communicationbiosynthetic processresponse to endogenous stimulusresponse to chemicalcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusestablishment of localizationcell cyclecellular localizationchromosome segregationanatomical structure developmentcellular component organizationnitrogen compound metabolic processcell communicationbiosynthetic processresponse to endogenous stimulusresponse to chemicalcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusestablishment of localizationcell cyclecellular localizationchromosome segregationanatomical structure developmentcellular component organizationnitrogen compound metabolic processcell communicationbiosynthetic processresponse to endogenous stimulusresponse to chemicalcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusestablishment of localizationcell cyclecellular localizationchromosome segregationanatomical structure developmentcellular component organizationnitrogen compound metabolic processcell communicationbiosynthetic processresponse to endogenous stimulusresponse to chemicalcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusestablishment of localizationcell cyclecellular localizationchromosome segregationanatomical structure developmentcellular component organizationnitrogen compound metabolic processcell communicationbiosynthetic processresponse to endogenous stimulusresponse to chemicalcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusestablishment of localizationcell cyclecellular localizationchromosome segregationanatomical structure developmentcellular component organizationnitrogen compound metabolic processcell communicationbiosynthetic processresponse to endogenous stimulusresponse to chemicalcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusestablishment of localizationcell cyclecellular localizationchromosome segregationanatomical structure developmentcellular component organizationnitrogen compound metabolic processcell communicationbiosynthetic processresponse to endogenous stimulusresponse to chemicalcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusestablishment of localizationcell cyclecellular localizationchromosome segregationanatomicaanatomical structure developmentcellular cellular component organizationnitrogen nitrogen compound metabolic processcell commcell communicationbiosynthebiosynthetic processresponse response to endogenous stimulusresponse response to chemicalcellular cellular metabolic processprimary mprimary metabolic processorganic sorganic substance metabolic processcellular cellular response to stimulusestablishestablishment of localizationcell cyclcell cyclecellular cellular localizationchromosomchromosome segregation
organic cyclic compound bindingheterocyclic compound bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingchromatin bindingorganic cyclic compound bindingheterocyclic compound bindingchromatin bindingorganic cyclic compound bindingorganic cyclic compound bindingheterocyclic compound bindingheterocyclic compound bindingchromatin bindingchromatin binding
cellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellmembraneorganellecellcellmembranemembraneorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006997 nucleus organization IEA
 biological_processGO:0006998 nuclear envelope organization IBA
 biological_processGO:0030514 negative regulation of BMP signaling pathway IBA
 biological_processGO:0070197 meiotic attachment of telomere to nuclear envelope IBA
 biological_processGO:1902531 regulation of intracellular signal transduction IEA
 cellular_componentGO:0005637 nuclear inner membrane IEA
 cellular_componentGO:0005639 integral component of nuclear inner membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0031490 chromatin DNA binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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