ENSDARG00000016570


Danio rerio
receptorprlraprolactinsignalinggrowthhormonemembraneactivitylonghematopoietinsinglechainconservedsitefibronectintypeiiiimmunoglobulin-likefolderythropoietinligandbindingpathwayintegralcomponentcytokineeyehead

Features
Gene ID: ENSDARG00000016570
  
Biological name :prlra
  
Synonyms : prlra / prolactin receptor a
  
Possible biological names infered from orthology : Gm21973 / P16471 / PRLR / prolactin receptor / Q08501
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 11105007
Gene end: 11135942
  
Corresponding Affymetrix probe sets: Dr.7609.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000153354
Ensembl peptide - ENSDARP00000111484
NCBI entrez gene - 407651     See in Manteia.
RefSeq - NM_001128677
RefSeq - XM_005161016
RefSeq - XM_021468801
RefSeq Peptide - NP_001122149
swissprot - F1QG81
swissprot - B3DI57
ZFIN ID - ZDB-GENE-080103-2
Ensembl - ENSDARG00000016570
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRLRENSGALG00000003446Gallus gallus
 PRLRENSG00000113494Homo sapiens
 Gm21973ENSMUSG00000094814Mus musculus
 PrlrENSMUSG00000005268Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prlrb / prolactin receptor b / PRLR* / P16471* / Q08501* / Gm21973* / prolactin receptor*ENSDARG0000004595526
ghrb / growth hormone receptor b / GHR* / P10912* / P16882* / growth hormone receptor* / Growth hormone receptor Growth hormone-binding protein*ENSDARG0000000767119
ghra / growth hormone receptor a / GHR* / P10912* / P16882* / growth hormone receptor* / Growth hormone receptor Growth hormone-binding protein*ENSDARG0000005477119
crlf1a / cytokine receptor-like factor 1a / CRLF1* / O75462* / Q9JM58* / cytokine receptor like factor 1*ENSDARG0000002436512
crlf1b / cytokine receptor-like factor 1b / CRLF1* / O75462* / Q9JM58* / cytokine receptor like factor 1*ENSDARG0000000636811


Protein motifs (from Interpro)
Interpro ID Name
 IPR003528  Long hematopoietin receptor, single chain, conserved site
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR015152  Growth hormone/erythropoietin receptor, ligand binding
 IPR033230  Prolactin receptor


Gene Ontology (GO)
cell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscell communicationcell communicationresponse to endogenous stimulusresponse to endogenous stimulusresponse to chemicalresponse to chemicalcellular response to stimuluscellular response to stimulus
signaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activity
membranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0038161 prolactin signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004896 cytokine receptor activity IEA
 molecular_functionGO:0004925 prolactin receptor activity IEA


Pathways (from Reactome)
Pathway description
Prolactin receptor signaling
Growth hormone receptor signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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