ENSDARG00000016782


Danio rerio

Features
Gene ID: ENSDARG00000016782
  
Biological name :huwe1
  
Synonyms : HECT, UBA and WWE domain containing 1 / huwe1
  
Possible biological names infered from orthology : E3 ubiquitin-protein ligase HUWE1 / HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase / Q7TMY8 / Q7Z6Z7
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 28494189
Gene end: 28568978
  
Corresponding Affymetrix probe sets: Dr.18821.1.S1_at (Zebrafish Array)   Dr.26506.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000002767
Ensembl peptide - ENSDARP00000118265
swissprot - E7F8Q5
swissprot - F1QL68
ZFIN ID - ZDB-GENE-081104-387
Ensembl - ENSDARG00000016782
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HUWE1ENSG00000086758Homo sapiens
 Huwe1ENSMUSG00000025261Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ubr5 / ubiquitin protein ligase E3 component n-recognin 5 / O95071*ENSDARG000000181929
AREL1 / apoptosis resistant E3 ubiquitin protein ligase 1 / O15033*ENSDARG000001003595


Protein motifs (from Interpro)
Interpro ID Name
 IPR000569  HECT domain
 IPR004170  WWE domain
 IPR009060  UBA-like superfamily
 IPR010309  E3 ubiquitin ligase, domain of unknown function DUF908
 IPR010314  E3 ubiquitin ligase, domain of unknown function DUF913
 IPR011989  Armadillo-like helical
 IPR015940  Ubiquitin-associated domain
 IPR016024  Armadillo-type fold
 IPR018123  WWE domain, subgroup
 IPR025527  Domain of unknown function DUF4414


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr