ENSDARG00000016999


Danio rerio

Features
Gene ID: ENSDARG00000016999
  
Biological name :lin28a
  
Synonyms : lin28a / lin-28 homolog A (C. elegans) / Q803L0
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 15440841
Gene end: 15473157
  
Corresponding Affymetrix probe sets: Dr.18118.1.S1_at (Zebrafish Array)   Dr.24217.1.S1_at (Zebrafish Array)   Dr.3862.1.A1_at (Zebrafish Array)   Dr.5094.3.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000126231
Ensembl peptide - ENSDARP00000150782
Ensembl peptide - ENSDARP00000148718
Ensembl peptide - ENSDARP00000089741
Ensembl peptide - ENSDARP00000113422
Ensembl peptide - ENSDARP00000116507
Ensembl peptide - ENSDARP00000125674
NCBI entrez gene - 394066     See in Manteia.
RefSeq - XM_005159535
swissprot - A0A0R4ISG0
swissprot - I3IS11
swissprot - I3ITG7
swissprot - Q803L0
swissprot - Z4YIC2
swissprot - A5PMB5
ZFIN ID - ZDB-GENE-040426-747
Ensembl - ENSDARG00000016999
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LIN28A / si:ch1073-284b18.2 / A * / Q8K3Y3* / Q9H9Z2* / lin-28 homolog A*ENSDARG0000000432865
lin28b / lin-28 homolog B (C. elegans) / Q6ZN17* / lin-28 homolog B*ENSDARG0000005251158


Protein motifs (from Interpro)
Interpro ID Name
 IPR001878  Zinc finger, CCHC-type
 IPR002059  Cold-shock protein, DNA-binding
 IPR011129  Cold shock domain
 IPR012156  Cold shock, CspA
 IPR012340  Nucleic acid-binding, OB-fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0010587 miRNA catabolic process ISS
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0019827 stem cell population maintenance ISS
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0031054 pre-miRNA processing ISS
 biological_processGO:0031099 regeneration IMP
 biological_processGO:0031123 RNA 3"-end processing ISS
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:2000767 positive regulation of cytoplasmic translation ISS
 cellular_componentGO:0000932 P-body ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005791 rough endoplasmic reticulum IEA
 cellular_componentGO:0005844 polysome ISS
 cellular_componentGO:0010494 cytoplasmic stress granule ISS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding ISS
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1905538 polysome binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism anterior-posterior axis decreased length , abnormal
whole organism dead , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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