Manteia

ENSDARG00000018616

Danio rerio

Features

Gene ID:	ENSDARG00000018616

Biological name :	agtr1a

Synonyms :	agtr1a / angiotensin II receptor, type 1a

Possible biological names infered from orthology :	AGTR1 / Agtr1b / angiotensin II receptor type 1 / P29754 / P29755 / P30556 / Type-1A angiotensin II receptor / Type-1B angiotensin II receptor

Species:	Danio rerio

Chr. number:	2
Strand:	1
Band:
Gene start:	24931677
Gene end:	24932753

Corresponding Affymetrix probe sets:

Cross references:	Ensembl peptide - ENSDARP00000009604 NCBI entrez gene - 794575 See in Manteia. swissprot - B0V116 ZFIN ID - ZDB-GENE-070912-546 Ensembl - ENSDARG00000018616

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
AGTR1	ENSGALG00000038512	Gallus gallus
AGTR1	ENSG00000144891	Homo sapiens
Agtr1a	ENSMUSG00000049115	Mus musculus
Agtr1b	ENSMUSG00000054988	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
agtr1b / angiotensin II receptor, type 1b / AGTR1* / P29755* / Agtr1a* / P29754* / P30556* / angiotensin II receptor type 1* / Type-1B angiotensin II receptor * / Type-1A angiotensin II receptor *	ENSDARG00000045443	56
agtr2 / angiotensin II receptor, type 2 / P35374* / P50052* / Type-2 angiotensin II receptor *	ENSDARG00000035552	35
Q7SZP9 / aplnra / apelin receptor a / APLNR* / Q9WV08* / P35414* / apelin receptor*	ENSDARG00000002172	33
A0T2N3 / aplnrb / apelin receptor b / APLNR* / Q9WV08* / P35414* / apelin receptor*	ENSDARG00000036670	32
rxfp3 / relaxin/insulin-like family peptide receptor 3 / Q8BGE9* / Q9NSD7* / Relaxin-3 receptor 1 *	ENSDARG00000057410	30
aplnr2 / apelin receptor 2	ENSDARG00000004447	29
gpr25 / G protein-coupled receptor 25 / O00155* / P0C5I1* / Probable G-protein coupled receptor 25 *	ENSDARG00000057112	29
rxfp3.2b / relaxin/insulin-like family peptide receptor 3.2b	ENSDARG00000061846	29
bdkrb1 / bradykinin receptor B1 / P46663* / Q61125* / B1 bradykinin receptor *	ENSDARG00000020744	28
si:dkey-63b1.1 / BDKRB2* / P30411* / P32299* / bradykinin receptor B2* / B2 bradykinin receptor *	ENSDARG00000043664	27
rxfp3.3b / relaxin/insulin-like family peptide receptor 3.3b / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000059348	27
rxfp3.3a2 / relaxin/insulin-like family peptide receptor 3.3a2 / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000062111	27
rxfp3.3a3 / relaxin/insulin-like family peptide receptor 3.3a3 / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000069246	27
rxfp3.3a1 / relaxin/insulin-like family peptide receptor 3.3a1 / RXFP4* / Q8TDU9* / Q7TQP4* / Relaxin-3 receptor 2 * / relaxin/insulin like family peptide receptor 4*	ENSDARG00000069028	25
ackr3b / atypical chemokine receptor 3b / ACKR3* / P25106* / P56485* / atypical chemokine receptor 3*	ENSDARG00000058179	24
ackr3a / atypical chemokine receptor 3a / ACKR3* / P25106* / P56485* / atypical chemokine receptor 3*	ENSDARG00000062478	24
gpr182 / G protein-coupled receptor 182 / O15218*	ENSDARG00000036616	22

Protein motifs (from Interpro)

Interpro ID	Name
IPR000190	Angiotensin II receptor type 1
IPR000248	Angiotensin II receptor family
IPR000276	G protein-coupled receptor, rhodopsin-like
IPR017452	GPCR, rhodopsin-like, 7TM

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0007165	signal transduction	IEA
biological_process	GO:0007186	G-protein coupled receptor signaling pathway	IEA
biological_process	GO:0019229	regulation of vasoconstriction	IEA
biological_process	GO:0038166	angiotensin-activated signaling pathway	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0004871	obsolete signal transducer activity	IEA
molecular_function	GO:0004930	G-protein coupled receptor activity	IEA
molecular_function	GO:0004945	angiotensin type II receptor activity	IEA

Pathways (from Reactome)

Pathway description

Peptide ligand-binding receptors

G alpha (q) signalling events

Cargo recognition for clathrin-mediated endocytosis

Clathrin-mediated endocytosis

Phenotype (from MGI, Zfin or HPO)

Phenotype

Definition

Genetic BG

No match

Interacting proteins (from Reactome)

Interactor ID	Name	Interaction type
ENSDARG00000016412	agt / angiotensinogen / P01019*	/ complex / reaction

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr