ENSDARG00000018881


Danio rerio

Features
Gene ID: ENSDARG00000018881
  
Biological name :apobec2a
  
Synonyms : apobec2a / apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a
  
Possible biological names infered from orthology : APOBEC2 / apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2 / apolipoprotein B mRNA editing enzyme catalytic subunit 2 / Q9WV35 / Q9Y235
  
Species: Danio rerio
  
Chr. number: 22
Strand: -1
Band:
Gene start: 641342
Gene end: 651719
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000124325
NCBI entrez gene - 503736     See in Manteia.
RefSeq - NM_001013314
RefSeq Peptide - NP_001013332
swissprot - F8W3Q7
ZFIN ID - ZDB-GENE-050306-15
Ensembl - ENSDARG00000018881
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 APOBEC2ENSGALG00000003226Gallus gallus
 Q9Y235ENSG00000124701Homo sapiens
 Q9WV35ENSMUSG00000040694Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
apobec2b / apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2b / Q9Y235* / APOBEC2* / apolipoprotein B mRNA editing enzyme catalytic subunit 2*ENSDARG0000011399255
aicda / activation-induced cytidine deaminase / Q9GZX7* / Q9WVE0* / Single-stranded DNA cytosine deaminase *ENSDARG0000001573423


Protein motifs (from Interpro)
Interpro ID Name
 IPR002125  Cytidine and deoxycytidylate deaminase domain
 IPR013158  APOBEC-like, N-terminal
 IPR016193  Cytidine deaminase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0031099 regeneration IGI
 biological_processGO:0043388 positive regulation of DNA binding IDA
 biological_processGO:0043697 cell dedifferentiation IMP
 biological_processGO:0060538 skeletal muscle organ development IMP
 biological_processGO:0070654 sensory epithelium regeneration IMP
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0000610 vertical myoseptum vertical myoseptum malformed , abnormal
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 ZFA:0001094 whole organism whole organism curved ventral , abnormal
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 ZFA:0001117 post-vent region post-vent region curved dorsal , abnormal
post-vent region curved ventral , abnormal
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 ZFA:0009115 skeletal muscle cell skeletal muscle cell increased length , abnormal
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 ZFA:0009280 Muller cell Muller cell cellular potency , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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