ENSDARG00000019096


Danio rerio

Features
Gene ID: ENSDARG00000019096
  
Biological name :myl7
  
Synonyms : myl7 / myosin, light chain 7, regulatory
  
Possible biological names infered from orthology : myosin light chain 7 / Myosin regulatory light chain 2, atrial isoform / Q01449 / Q9QVP4
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 40457107
Gene end: 40464935
  
Corresponding Affymetrix probe sets: Dr.642.1.S1_at (Zebrafish Array)   NM_131329_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000040012
NCBI entrez gene - 30592     See in Manteia.
RefSeq - NM_131329
RefSeq Peptide - NP_571404
swissprot - Q801M3
ZFIN ID - ZDB-GENE-991019-3
Ensembl - ENSDARG00000019096
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYL7ENSG00000106631Homo sapiens
 Myl7ENSMUSG00000020469Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
myl10 / myosin, light chain 10, regulatory / Q9BUA6* / myosin light chain 10*ENSDARG0000006259265
mylpfb / myosin light chain, phosphorylatable, fast skeletal muscle b / MYLPF* / Q96A32* / P97457* / myosin light chain, phosphorylatable, fast skeletal muscle* / Mus musculus myosin light ...ENSDARG0000000258963
mylpfa / myosin light chain, phosphorylatable, fast skeletal muscle a / MYLPF* / Q96A32* / P97457* / myosin light chain, phosphorylatable, fast skeletal muscle* / Mus musculus myosin light ...ENSDARG0000005325462
myl2b / myosin, light chain 2b, regulatory, cardiac, slow / MYL2* / P10916* / P51667* / myosin light chain 2* / Myosin regulatory light chain 2, ventricular/cardiac muscle isoform *ENSDARG0000005342462
CABZ01076669.1 / MYL2* / P10916* / myosin light chain 2*ENSDARG0000010472260
myl12.2 / myosin, light chain 12, genome duplicate 2 / Q3THE2* / MYL12A* / MYL12B* / O14950* / P19105* / myosin light chain 12A* / myosin light chain 12B* / Myosin regulatory light chain 12B *ENSDARG0000002532656
myl9a / myosin, light chain 9a, regulatory / Myl9* / Q9CQ19* / Myosin regulatory light polypeptide 9 *ENSDARG0000003812356
myl12.1 / myosin, light chain 12, genome duplicate 1ENSDARG0000009976656
myl9b / myosin, light chain 9b, regulatoryENSDARG0000000803054


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045214 sarcomere organization IMP
 biological_processGO:0045823 positive regulation of heart contraction IMP
 biological_processGO:0048738 cardiac muscle tissue development IMP
 biological_processGO:0055004 atrial cardiac myofibril assembly IMP
 biological_processGO:0055005 ventricular cardiac myofibril assembly IMP
 biological_processGO:0055015 ventricular cardiac muscle cell development IMP
 biological_processGO:0060038 cardiac muscle cell proliferation IMP
 biological_processGO:0060047 heart contraction IMP
 molecular_functionGO:0005509 calcium ion binding IEA


Pathways (from Reactome)
Pathway description
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle increased size , abnormal
cardiac ventricle decreased volume , abnormal
cardiac ventricle decreased contractility , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart quality , abnormal
heart contractility , abnormal
Show

 ZFA:0009316 cardiac muscle cell cardiac muscle cell sarcomere decreased length , abnormal
cardiac muscle cell shape , abnormal
cardiac muscle cell decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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