ENSDARG00000019260


Danio rerio

Features
Gene ID: ENSDARG00000019260
  
Biological name :dhrs9
  
Synonyms : dehydrogenase/reductase (SDR family) member 9 / dhrs9
  
Possible biological names infered from orthology : dehydrogenase/reductase 9 / Q58NB6 / Q9BPW9
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 48706038
Gene end: 48736388
  
Corresponding Affymetrix probe sets: Dr.2961.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000027139
swissprot - F1QJC1
ZFIN ID - ZDB-GENE-030131-1249
Ensembl - ENSDARG00000019260
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DHRS9ENSGALG00000010873Gallus gallus
 DHRS9ENSG00000073737Homo sapiens
 Dhrs9ENSMUSG00000027068Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rdh5 / retinol dehydrogenase 5 (11-cis/9-cis) / Q92781* / O55240* / retinol dehydrogenase 5* / Mus musculus retinol dehydrogenase 5 (Rdh5), transcript variant 2, mRNA.*ENSDARG0000000830651
rdh1 / retinol dehydrogenase 1ENSDARG0000001788250
bdh1 / 3-hydroxybutyrate dehydrogenase, type 1 / Q80XN0* / Q02338* / 3-hydroxybutyrate dehydrogenase 1* / D-beta-hydroxybutyrate dehydrogenase, mitochondrial *ENSDARG0000005938835
zgc:113142ENSDARG0000003896932
hsd11b2 / hydroxysteroid (11-beta) dehydrogenase 2 / P51661* / P80365*ENSDARG0000000197530
hsd17b2 / hydroxysteroid (17-beta) dehydrogenase 2 / P37059* / P51658*ENSDARG0000004555327
hsd17b1 / hydroxysteroid (17-beta) dehydrogenase 1 / P14061* / P51656*ENSDARG0000002746919
rdh8a / retinol dehydrogenase 8a / RDH8* / retinol dehydrogenase 8 (all-trans)*ENSDARG0000002804819
rdh8b / retinol dehydrogenase 8b / RDH8* / retinol dehydrogenase 8 (all-trans)*ENSDARG0000010506019
dhrs7 / dehydrogenase/reductase (SDR family) member 7 / Gm4756* / Q9CXR1* / Q9Y394* / dehydrogenase/reductase 7*ENSDARG0000000344418
dhrs7b / dehydrogenase/reductase (SDR family) member 7B / Q6IAN0* / Q99J47* / dehydrogenase/reductase 7B*ENSDARG0000007572618
zgc:109982ENSDARG0000009921718
zmp:0000001048ENSDARG0000001621317
kdsr / 3-ketodihydrosphingosine reductase / Q06136* / Q6GV12*ENSDARG0000001202116
A8E5C5 / dhrs7cb / dehydrogenase/reductase (SDR family) member 7Cb / Q8CHS7* / DHRS7C* / A6NNS2* / dehydrogenase/reductase 7C* / Dehydrogenase/reductase SDR family member 7C *ENSDARG0000007187716
dhrs7ca / dehydrogenase/reductase (SDR family) member 7Ca / Q8CHS7* / DHRS7C* / A6NNS2* / dehydrogenase/reductase 7C* / Dehydrogenase/reductase SDR family member 7C *ENSDARG0000003945315


Protein motifs (from Interpro)
Interpro ID Name
 IPR002347  Short-chain dehydrogenase/reductase SDR
 IPR016040  NAD(P)-binding domain
 IPR020904  Short-chain dehydrogenase/reductase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0014032 neural crest cell development IMP
 biological_processGO:0031017 exocrine pancreas development IMP
 biological_processGO:0035138 pectoral fin morphogenesis IMP
 biological_processGO:0042572 retinol metabolic process IDA
 biological_processGO:0042574 retinal metabolic process IDA
 biological_processGO:0048546 digestive tract morphogenesis IMP
 biological_processGO:0048703 embryonic viscerocranium morphogenesis IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060047 heart contraction IMP
 molecular_functionGO:0004745 retinol dehydrogenase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA


Pathways (from Reactome)
Pathway description
The canonical retinoid cycle in rods (twilight vision)
RA biosynthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000114 heart heart decreased functionality , abnormal
heart decreased contractility , abnormal
Show

 ZFA:0000140 pancreas pancreas molecular quality , abnormal
Show

 ZFA:0000471 atrium atrium decreased size , abnormal
Show

 ZFA:0001076 intestinal bulb intestinal bulb hypoplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
Show

 ZFA:0001117 post-vent region post-vent region curved ventral , abnormal
Show

 ZFA:0001161 pectoral fin pectoral fin absent , abnormal
Show

 ZFA:0001227 mandibular arch skeleton mandibular arch skeleton absent , abnormal
Show

 ZFA:0001338 intestine intestine molecular quality , abnormal
intestine morphology , abnormal
intestine lacks all parts of type intestinal villus , abnormal
intestine lacks all parts of type columnar/cuboidal epithelial cell , abnormal
Show

 ZFA:0005124 intestinal epithelium intestinal epithelium aplastic , abnormal
Show

 ZFA:0009165 neural crest cell neural crest cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr