ENSDARG00000021208


Danio rerio

Features
Gene ID: ENSDARG00000021208
  
Biological name :serpind1
  
Synonyms : serpind1 / serpin peptidase inhibitor, clade D (heparin cofactor), member 1
  
Possible biological names infered from orthology : P05546 / P49182 / serine (or cysteine) peptidase inhibitor, clade D, member 1 / serpin family D member 1
  
Species: Danio rerio
  
Chr. number: 8
Strand: 1
Band:
Gene start: 1766206
Gene end: 1781733
  
Corresponding Affymetrix probe sets: Dr.4865.1.A1_at (Zebrafish Array)   NM_182880_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000073528
Ensembl peptide - ENSDARP00000017995
NCBI entrez gene - 359841     See in Manteia.
RefSeq - NM_182880
RefSeq - XM_005166737
RefSeq Peptide - NP_878300
swissprot - B0V3R7
ZFIN ID - ZDB-GENE-030711-2
Ensembl - ENSDARG00000021208
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SERPIND1ENSGALG00000039239Gallus gallus
 P05546ENSG00000099937Homo sapiens
 P49182ENSMUSG00000022766Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
serpina1 / serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 / P05154* / P05543* / P07758* / P08185* / P22599* / P29621* / P29622* / P70458* / Q00897* / Q0...ENSDARG0000009028625
serpina1l / serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like / P05543* / P07758* / P08185* / P22599* / P29621* / P29622* / P70458* / ...ENSDARG0000009085025
si:ch211-186e20.2 / P05154* / P05543* / P07758* / P08185* / P22599* / P29621* / P29622* / P70458* / Q00897* / P01009* / Q03734* / Q06770* / Q6P4P1* / Q7TMF5* / Q80X76* / Q86U17* / Q86WD7* /...ENSDARG0000007471222
si:ch1073-416d2.3 / Q9UK55* / Q8R121* / SERPINA10* / serpin family A member 10* / Protein Z-dependent protease inhibitor *ENSDARG0000003696821
si:ch211-186e20.7 / P05154* / P05543* / P07758* / P08185* / P22599* / P29621* / P29622* / P70458* / Q00897* / P01009* / Q03734* / Q06770* / Q6P4P1* / Q7TMF5* / Q80X76* / Q86U17* / Q86WD7* /...ENSDARG0000007796021
serpina7 / serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 / P05543* / P07758* / P08185* / P22599* / P29621* / P29622* / P70458* / Q00897* / Q00898* / Q0...ENSDARG0000008714321
zgc:174259 / P05154* / P05543* / P07758* / P08185* / P22599* / P29621* / P29622* / P70458* / Q00897* / P01009* / Q03734* / Q06770* / Q6P4P1* / Q7TMF5* / Q80X76* / Q86U17* / Q86WD7* / Q8BYY9...ENSDARG0000009113621
serpina10a / serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a / Q9UK55* / Q8R121* / SERPINA10* / serpin family A member 10* / Protein Z-dependent protea...ENSDARG0000000592420


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain
 IPR033831  Heparin cofactor II


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000036041 f2 / coagulation factor II (thrombin) / P00734* / P19221* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*  / complex / reaction






 

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