ENSDARG00000024771


Danio rerio

Features
Gene ID: ENSDARG00000024771
  
Biological name :slc24a5
  
Synonyms : slc24a5 / solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
  
Possible biological names infered from orthology : Q71RS6 / Q8C261 / solute carrier family 24 member 5
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 5213338
Gene end: 5227420
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000030499
NCBI entrez gene - 570312     See in Manteia.
RefSeq - NM_001030280
RefSeq Peptide - NP_001025451
swissprot - B0V3S7
ZFIN ID - ZDB-GENE-031210-1
Ensembl - ENSDARG00000024771
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SLC24A5ENSGALG00000004885Gallus gallus
 Q71RS6ENSG00000188467Homo sapiens
 Q8C261ENSMUSG00000035183Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
slc24a4a / solute carrier family 24 (sodium/potassium/calcium exchanger), member 4a / Q8NFF2* / SLC24A4* / solute carrier family 24 member 4* / solute carrier family 24 (sodium/potassium/ca...ENSDARG0000001542540
slc24a3 / solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 / Q99PD7* / Q9HC58* / solute carrier family 24 member 3*ENSDARG0000000676039
si:ch73-335m24.5ENSDARG0000003638339
slc24a4b / solute carrier family 24 (sodium/potassium/calcium exchanger), member 4b / Q8NFF2* / SLC24A4* / solute carrier family 24 member 4* / solute carrier family 24 (sodium/potassium/ca...ENSDARG0000006750939
LO018380.1ENSDARG0000004108637
slc24a1 / solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 / O60721* / solute carrier family 24 member 1*ENSDARG0000004143133
slc24a2 / solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 / Q9UI40* / solute carrier family 24 member 2*ENSDARG0000004298832
CABZ01081780.1 / Q9UI40* / SLC24A2* / solute carrier family 24 member 2* / solute carrier family 24 (sodium/potassium/calcium exchanger), member 2*ENSDARG0000006315831
slc8b1 / solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 / Q6J4K2* / Q925Q3* / solute carrier family 8 member B1*ENSDARG000001055848


Protein motifs (from Interpro)
Interpro ID Name
 IPR004481  Sodium/potassium/calcium exchanger
 IPR004837  Sodium/calcium exchanger membrane region
 IPR030245  Sodium/potassium/calcium exchanger 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0048021 regulation of melanin biosynthetic process IEA
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0097324 melanocyte migration IMP
 cellular_componentGO:0005802 trans-Golgi network IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0008273 calcium, potassium:sodium antiporter activity IEA


Pathways (from Reactome)
Pathway description
Sodium/Calcium exchangers


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain edematous , abnormal
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 ZFA:0000012 central nervous system central nervous system damage , ameliorated
central nervous system damaged , abnormal
Show

 ZFA:0000028 heart primordium heart primordium unfused from heart primordium , abnormal
heart primordium myocardial precursor decreased amount , abnormal
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 ZFA:0000029 hindbrain hindbrain morphology , abnormal
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 ZFA:0000075 spinal cord spinal cord structure , abnormal
spinal cord curvature , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0000144 retinal pigmented epithelium retinal pigmented epithelium pigment granule decreased amount , abnormal
retinal pigmented epithelium quality , abnormal
retinal pigmented epithelium unpigmented , abnormal
retinal pigmented epithelium decreased pigmentation , abnormal
retinal pigmented epithelium melanosome decreased pigmentation , abnormal
retinal pigmented epithelium color , abnormal
retinal pigmented epithelium degree of pigmentation , ameliorated
Show

 ZFA:0000360 heart tube heart tube absent , abnormal
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 ZFA:0000368 integument integument melanocyte decreased amount , abnormal
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 ZFA:0001058 caudal fin caudal fin melanocyte decreased pigmentation , abnormal
caudal fin melanocyte degree of pigmentation , ameliorated
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 ZFA:0001094 whole organism whole organism Melanin decreased amount , abnormal
whole organism decreased life span , abnormal
whole organism decreased pigmentation , abnormal
whole organism degree of pigmentation , ameliorated
whole organism increased amount , abnormal
whole organism decreased length , abnormal
whole organism dead , abnormal
whole organism deformed , abnormal
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 ZFA:0001114 head head swollen , abnormal
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 ZFA:0001162 anal fin anal fin has fewer parts of type melanocyte , abnormal
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 ZFA:0001463 melanophore stripe melanophore stripe decreased pigmentation , abnormal
melanophore stripe degree of pigmentation , ameliorated
Show

 ZFA:0001479 lateral line nerve lateral line nerve myelin sheath absent , abnormal
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 ZFA:0009052 motor neuron motor neuron axon decreased length , abnormal
motor neuron axon decreased thickness , abnormal
motor neuron axon hypoplastic , abnormal
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 ZFA:0009090 pigment cell pigment cell quality , abnormal
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 ZFA:0009091 melanocyte melanocyte intensity , abnormal
melanocyte unpigmented , abnormal
melanocyte decreased pigmentation , abnormal
melanocyte absent , abnormal
melanocyte low saturation , abnormal
melanocyte quality , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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