ENSDARG00000027724


Danio rerio
kinasedgkbdomaindiacylglycerolactivityef-handbindingproteinnadn-terminalsignaltransductionintracellularaccessorycatalyticc-likephorbolesterdiacylglycerol-bindingpairkinase-likesuperfamilyinorganicpolyphosphateatp-nadcalcium-bindingsitetypec-activatingg-proteincoupled

Features
Gene ID: ENSDARG00000027724
  
Biological name :dgkb
  
Synonyms : dgkb / diacylglycerol kinase, beta
  
Possible biological names infered from orthology : Q6NS52 / Q9Y6T7
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 34215796
Gene end: 34326461
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000150783
Ensembl peptide - ENSDARP00000018318
Ensembl peptide - ENSDARP00000129287
Ensembl peptide - ENSDARP00000151149
swissprot - X1WGD2
swissprot - E7F297
ZFIN ID - ZDB-GENE-070126-1
Ensembl - ENSDARG00000027724
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DGKBENSGALG00000033561Gallus gallus
 DGKBENSG00000136267Homo sapiens
 DgkbENSMUSG00000036095Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
dgkg / diacylglycerol kinase, gamma / P49619* / Q91WG7*ENSDARG0000006269664
dgkaa / diacylglycerol kinase, alpha a / DGKA* / O88673* / P23743* / diacylglycerol kinase alpha* / Mus musculus diacylglycerol kinase, alpha (Dgka), transcript variant 2, mRNA.*ENSDARG0000006062654
dgkab / diacylglycerol kinase, alpha b / DGKA* / O88673* / P23743* / diacylglycerol kinase alpha* / Mus musculus diacylglycerol kinase, alpha (Dgka), transcript variant 2, mRNA.*ENSDARG0000009817547
dgkh / diacylglycerol kinase, eta / Q86XP1*ENSDARG0000001871626
si:dkey-172j4.3ENSDARG0000007418325
dgkza / diacylglycerol kinase, zeta a / DGKZ* / Q13574* / Q80UP3* / diacylglycerol kinase zeta*ENSDARG0000001443923
dgkzb / diacylglycerol kinase, zeta b / DGKZ* / Q13574* / Q80UP3* / diacylglycerol kinase zeta*ENSDARG0000007602522
dgke / diacylglycerol kinase, epsilon / P52429* / Q9R1C6*ENSDARG0000010479322
CABZ01020835.1 / DGKI* / O75912* / diacylglycerol kinase iota*ENSDARG0000006357821
DGKD / diacylglycerol kinase delta / Q16760*ENSDARG000001131116


Protein motifs (from Interpro)
Interpro ID Name
 IPR000756  Diacylglycerol kinase, accessory domain
 IPR001206  Diacylglycerol kinase, catalytic domain
 IPR002048  EF-hand domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR011992  EF-hand domain pair
 IPR016064  NAD kinase/diacylglycerol kinase-like domain superfamily
 IPR017438  Inorganic polyphosphate/ATP-NAD kinase, N-terminal
 IPR018247  EF-Hand 1, calcium-binding site
 IPR029477  Diacylglycerol kinase type I, N-terminal


Gene Ontology (GO)
cell communicationcellular response to stimuluscellular metabolic processcell communicationcellular response to stimuluscellular metabolic processcell communicationcellular response to stimuluscellular metabolic processcell communicationcellular response to stimuluscellular metabolic processcell communicationcellular response to stimuluscellular metabolic processcell communicationcellular response to stimuluscellular metabolic processcell communicationcellular response to stimuluscellular metabolic processcell communicationcellular response to stimuluscellular metabolic processcell communicationcellular response to stimuluscellular metabolic processcell communicationcellular response to stimuluscellular metabolic processcell communicationcell communicationcellular response to stimuluscellular response to stimuluscellular metabolic processcellular metabolic process
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingtransferase activityion bindingcarbohydrate derivative bindingdrug bindingorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingsmall molecule bindismall molecule bindingtransferase activitytransferase activityion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingdrug bindingdrug binding
cellcellcellcellcellcellcellcellcellcellcellcell
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 cellular_componentGO:0005622 intracellular IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003951 NAD+ kinase activity IEA
 molecular_functionGO:0004143 diacylglycerol kinase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Effects of PIP2 hydrolysis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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