ENSDARG00000030789


Danio rerio

Features
Gene ID: ENSDARG00000030789
  
Biological name :ddx18
  
Synonyms : ddx18 / DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
  
Possible biological names infered from orthology : ATP-dependent RNA helicase DDX18 / DEAD-box helicase 18 / Q8K363 / Q9NVP1
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 38314466
Gene end: 38352220
  
Corresponding Affymetrix probe sets: Dr.24235.1.A1_at (Zebrafish Array)   Dr.24235.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000048752
swissprot - F1QLW8
ZFIN ID - ZDB-GENE-030131-9685
Ensembl - ENSDARG00000030789
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DDX18ENSGALG00000012147Gallus gallus
 DDX18ENSG00000088205Homo sapiens
 Ddx18ENSMUSG00000001674Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000629  ATP-dependent RNA helicase DEAD-box, conserved site
 IPR001650  Helicase, C-terminal
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR014014  RNA helicase, DEAD-box type, Q motif
 IPR025313  Domain of unknown function DUF4217
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010501 RNA secondary structure unwinding IBA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030099 myeloid cell differentiation IMP
 cellular_componentGO:0005730 nucleolus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004004 ATP-dependent RNA helicase activity IBA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain necrotic , abnormal
brain edematous , abnormal
Show

 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
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 ZFA:0000014 dorsal aorta dorsal aorta hematopoietic stem cell decreased amount , abnormal
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 ZFA:0000029 hindbrain hindbrain quality , abnormal
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 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary quality , abnormal
midbrain hindbrain boundary condensed , abnormal
Show

 ZFA:0000094 blood island blood island hematopoietic stem cell decreased amount , abnormal
Show

 ZFA:0000106 extension extension shortened , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000110 fourth ventricle fourth ventricle distended , abnormal
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 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
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 ZFA:0000123 liver liver quality , abnormal
liver hypoplastic , abnormal
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 ZFA:0001094 whole organism whole organism dead , abnormal
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 ZFA:0001114 head head decreased width , abnormal
head decreased size , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel hypoplastic , abnormal
Show

 ZFA:0009256 nucleate erythrocyte nucleate erythrocyte decreased amount , abnormal
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 ZFA:0009309 leukocyte leukocyte decreased amount , abnormal
Show

 ZFA:0009324 myeloid cell myeloid cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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