ENSDARG00000031348


Danio rerio
receptormc5ramelanocortinmembraneactivitygrhodopsin-likesignalg-proteincoupledprotein-coupledacthgpcrtmtransductionsignalingpathwayplasmaintegralcomponentobsoletetransducerpeptideligand-bindingreceptorsalphassignallingevents

Features
Gene ID: ENSDARG00000031348
  
Biological name :mc5ra
  
Synonyms : mc5ra / melanocortin 5a receptor
  
Possible biological names infered from orthology : MC5R / melanocortin 5 receptor / P33032
  
Species: Danio rerio
  
Chr. number: 19
Strand: 1
Band:
Gene start: 12762887
Gene end: 12803408
  
Corresponding Affymetrix probe sets: Dr.20031.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000040072
Ensembl peptide - ENSDARP00000120348
NCBI entrez gene - 286834     See in Manteia.
swissprot - A3KGQ1
swissprot - Q8JGW2
ZFIN ID - ZDB-GENE-021223-3
Ensembl - ENSDARG00000031348
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MC5RENSGALG00000032087Gallus gallus
 MC5RENSG00000176136Homo sapiens
 Mc5rENSMUSG00000007480Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mc5rb / melanocortin 5b receptor / MC5R* / P33032* / melanocortin 5 receptor*ENSDARG0000005494676
mc4r / B0V1P1 / melanocortin 4 receptor / P32245* / P56450* / Melanocortin receptor 4 *ENSDARG0000001551567
mc3r / melanocortin 3 receptor / P33033* / P41968* / Melanocortin receptor 3 *ENSDARG0000002136963
mc1r / melanocortin 1 receptor / Q01727* / Melanocyte-stimulating hormone receptor *ENSDARG0000002023750
mc2r / melanocortin 2 receptor / Q01718* / Q64326*ENSDARG0000005494938


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000621  Melanocortin 5 receptor
 IPR001671  Melanocortin/ACTH receptor
 IPR001908  Melanocortin receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
cell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcellular response to stimuluscell communicationcell communicationcellular response to stimuluscellular response to stimulus
signaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activitysignaling receptor activity
cellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellmembranecellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004977 melanocortin receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000043135 pomca / proopiomelanocortin a / POMC* / P01193* / P01189* / proopiomelanocortin* / pro-opiomelanocortin-alpha*  / complex / reaction
 ENSDARG00000069307 pomcb / proopiomelanocortin b / POMC* / P01193* / P01189* / proopiomelanocortin* / pro-opiomelanocortin-alpha*  / complex / reaction






 

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