ENSDARG00000032831


Danio rerio

Features
Gene ID: ENSDARG00000032831
  
Biological name :htra1a
  
Synonyms : htra1a / HtrA serine peptidase 1a / Q6GMI0
  
Possible biological names infered from orthology : HTRA1 / HtrA serine peptidase 1 / Q92743 / Q9R118 / Serine protease HTRA1
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 21919131
Gene end: 21959556
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000048135
NCBI entrez gene - 431766     See in Manteia.
RefSeq - NM_001002219
RefSeq Peptide - NP_001002219
swissprot - B2GT42
swissprot - Q6GMI0
ZFIN ID - ZDB-GENE-040704-64
Ensembl - ENSDARG00000032831
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HTRA1ENSGALG00000041140Gallus gallus
 HTRA1ENSG00000166033Homo sapiens
 Htra1ENSMUSG00000006205Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
htra1b / A9JRB3 / HtrA serine peptidase 1b / HTRA1* / Q9R118* / Q92743* / Serine protease HTRA1 * / HtrA serine peptidase 1*ENSDARG0000001490780
htra4 / HtrA serine peptidase 4 / A2RT60* / P83105* / Serine protease HTRA4 *ENSDARG0000000594358
htra3a / HtrA serine peptidase 3a / HTRA3* / P83110* / Q9D236* / Serine protease HTRA3 * / HtrA serine peptidase 3*ENSDARG0000005289551
HTRA3 / HtrA serine peptidase 3 / P83110*ENSDARG0000001092547
si:dkey-33c12.12 / si:dkey-112g5.12 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000006990941
zgc:174193 / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000008874334
si:dkey-265c15.6 / si:dkey-112g5.12 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000007671332
si:dkey-112g5.16 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009220224
si:dkey-84o3.7 / si:dkey-84o3.3 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000007013823
si:dkey-112g5.13 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009206123
si:dkey-112g5.12 / si:dkey-112g5.11 / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009209423
si:dkey-84o3.7 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009213323
si:dkey-33c12.14 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009238023
si:dkey-33c12.11 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009300523
zgc:173425 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009474123
si:dkey-19p15.4 / si:dkey-112g5.14 / HTRA2 (1 of many) / HTRA2* / Q9JIY5* / O43464* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009531423
si:dkey-33c12.12 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009554523
si:dkey-84o3.7 / si:dkey-84o3.3 / HTRA2 (1 of many) / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000009568723
si:dkey-19p15.4 / HTRA2* / O43464* / Q9JIY5* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000011163323
CR848040.4 / HTRA2* / Q9JIY5* / O43464* / HtrA serine peptidase 2* / Serine protease HTRA2, mitochondrial *ENSDARG0000011510623


Protein motifs (from Interpro)
Interpro ID Name
 IPR000867  Insulin-like growth factor-binding protein, IGFBP
 IPR001478  PDZ domain
 IPR001940  Peptidase S1C
 IPR002350  Kazal domain
 IPR009003  Peptidase S1, PA clan
 IPR009030  Growth factor receptor cysteine-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IEA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0040036 regulation of fibroblast growth factor receptor signaling pathway IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0005520 insulin-like growth factor binding IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019838 growth factor binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000155 somite somite increased size , abnormal
Show

 ZFA:0001058 caudal fin caudal fin kinked , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased length , abnormal
whole organism wholly dorsalized , abnormal
whole organism elongated , abnormal
Show

 ZFA:0001605 caudal fin lower lobe caudal fin lower lobe absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr