ENSDARG00000033852


Danio rerio
spindlemad1l1mitoticassemblycheckpointmadkinetochoresignalsistercomponentattachmentmicrotubulesnuclearenvelopemolecularfunctionamplificationunattachedkinetochoresviainhibitoryseparationchromatidsresolutionchromatidcohesionrhogtpasesactivateformins

Features
Gene ID: ENSDARG00000033852
  
Biological name :mad1l1
  
Synonyms : mad1l1 / mitotic arrest deficient 1 like 1
  
Possible biological names infered from orthology : Mus musculus MAD1 mitotic arrest deficient 1-like 1 (Mad1l1), transcript variant 2, mRNA. / Q9WTX8 / Q9Y6D9
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 9739370
Gene end: 9858508
  
Corresponding Affymetrix probe sets: Dr.19494.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000123048
NCBI entrez gene - 393886     See in Manteia.
swissprot - D9IWE2
ZFIN ID - ZDB-GENE-040426-1081
Ensembl - ENSDARG00000033852
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MAD1L1ENSGALG00000004224Gallus gallus
 MAD1L1ENSG00000002822Homo sapiens
 Mad1l1ENSMUSG00000029554Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008672  Spindle assembly checkpoint component Mad1


Gene Ontology (GO)
cellular component organizationcell cyclechromosome segregationestablishment of localizationcellular localizationcellular component organizationcell cyclechromosome segregationestablishment of localizationcellular localizationcellular component organizationcell cyclechromosome segregationestablishment of localizationcellular localizationcellular component organizationcell cyclechromosome segregationestablishment of localizationcellular localizationcellular component organizationcell cyclechromosome segregationestablishment of localizationcellular localizationcellular component organizationcell cyclechromosome segregationestablishment of localizationcellular localizationcellular component organizationcell cyclechromosome segregationestablishment of localizationcellular localizationcellular component organizationcell cyclechromosome segregationestablishment of localizationcellular localizationcellular component organizationcell cyclechromosome segregationestablishment of localizationcellular localizationcellular component organizationcell cyclechromosome segregationestablishment of localizationcellular localizationcellular component organizatcellular component organizationcell cyclecell cyclechromosome segregationchromosome segregationestablishment of localizatioestablishment of localizationcellular localizationcellular localization
cellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellprotein-containing complexorganellecellcellprotein-containing complexprotein-containing complexorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0007094 mitotic spindle assembly checkpoint IBA
 biological_processGO:0051315 attachment of mitotic spindle microtubules to kinetochore IBA
 cellular_componentGO:0000776 kinetochore IBA
 cellular_componentGO:0005635 nuclear envelope IBA
 cellular_componentGO:0072686 mitotic spindle IBA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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