ENSDARG00000034270


Danio rerio

Features
Gene ID: ENSDARG00000034270
  
Biological name :ogdha
  
Synonyms : ogdha / oxoglutarate (alpha-ketoglutarate) dehydrogenase a (lipoamide)
  
Possible biological names infered from orthology : 2-oxoglutarate dehydrogenase, mitochondrial / OGDH / oxoglutarate dehydrogenase / Q02218 / Q60597
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 45762484
Gene end: 45838481
  
Corresponding Affymetrix probe sets: Dr.15381.1.S1_at (Zebrafish Array)   Dr.901.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000113397
Ensembl peptide - ENSDARP00000138115
Ensembl peptide - ENSDARP00000121989
Ensembl peptide - ENSDARP00000009474
Ensembl peptide - ENSDARP00000046063
NCBI entrez gene - 564552     See in Manteia.
RefSeq - NM_200779
RefSeq Peptide - NP_957073
swissprot - F1Q5B8
swissprot - F1RAH0
swissprot - Q6PBQ6
swissprot - B8JI08
swissprot - A0A0R4IP01
ZFIN ID - ZDB-GENE-030131-2143
Ensembl - ENSDARG00000034270
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 OGDHENSGALG00000014155Gallus gallus
 OGDHENSG00000105953Homo sapiens
 OgdhENSMUSG00000020456Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ogdhb / oxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide) / OGDH* / Q60597* / Q02218* / oxoglutarate dehydrogenase* / 2-oxoglutarate dehydrogenase, mitochondrial *ENSDARG0000010342867
ogdhl / oxoglutarate dehydrogenase like / Q9ULD0*ENSDARG0000007924936
dhtkd1 / dehydrogenase E1 and transketolase domain containing 1 / A2ATU0* / Q96HY7* / Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial *ENSDARG0000001641512


Protein motifs (from Interpro)
Interpro ID Name
 IPR001017  Dehydrogenase, E1 component
 IPR005475  Transketolase-like, pyrimidine-binding domain
 IPR011603  2-oxoglutarate dehydrogenase E1 component
 IPR029061  Thiamin diphosphate-binding fold
 IPR031717  Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal
 IPR032106  2-oxoglutarate dehydrogenase E1 component, N-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060047 heart contraction IGI
 cellular_componentGO:0005739 mitochondrion IBA
 cellular_componentGO:0045252 oxoglutarate dehydrogenase complex IBA
 molecular_functionGO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity IEA
 molecular_functionGO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEA
 molecular_functionGO:0030976 thiamine pyrophosphate binding IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Lysine catabolism
Citric acid cycle (TCA cycle)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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