ENSDARG00000034307


Danio rerio

Features
Gene ID: ENSDARG00000034307
  
Biological name :chrne
  
Synonyms : cholinergic receptor, nicotinic, epsilon / chrne
  
Possible biological names infered from orthology : cholinergic receptor, nicotinic, epsilon polypeptide / cholinergic receptor nicotinic epsilon subunit / P20782 / Q04844
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 38440099
Gene end: 38451082
  
Corresponding Affymetrix probe sets: Dr.15266.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000116514
NCBI entrez gene - 445315     See in Manteia.
RefSeq - NM_001327883
RefSeq Peptide - NP_001314812
swissprot - A2BG85
ZFIN ID - ZDB-GENE-040808-32
Ensembl - ENSDARG00000034307
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CHRNEENSG00000108556Homo sapiens
 ChrneENSMUSG00000014609Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
chrng / cholinergic receptor, nicotinic, gamma / P07510* / cholinergic receptor nicotinic gamma subunit*ENSDARG0000008664755
chrnd / cholinergic receptor, nicotinic, delta (muscle) / P02716* / Q07001* / cholinergic receptor nicotinic delta subunit* / cholinergic receptor, nicotinic, delta polypeptide*ENSDARG0000001934248
chrnb1l / cholinergic receptor, nicotinic, beta 1 (muscle) like / CHRNB1* / P09690* / P11230* / cholinergic receptor nicotinic beta 1 subunit* / cholinergic receptor, nicotinic, beta polype...ENSDARG0000002253238
chrnb1 / cholinergic receptor, nicotinic, beta 1 (muscle) / P09690* / P11230* / cholinergic receptor nicotinic beta 1 subunit* / cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)*ENSDARG0000006966035
FO907089.1 / Q494W8* / CHRNA7* / P36544* / CHRFAM7A* / cholinergic receptor nicotinic alpha 7 subunit* / CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion*ENSDARG0000010152228
chrna7 / cholinergic receptor, nicotinic, alpha 7 (neuronal) / Q494W8* / P36544* / P49582* / CHRFAM7A* / cholinergic receptor nicotinic alpha 7 subunit* / CHRNA7 (exons 5-10) and FAM7A (exo...ENSDARG0000010170226
si:ch211-39a7.1ENSDARG0000003742725
si:ch73-380n15.2ENSDARG0000008722425
chrna9 / cholinergic receptor, nicotinic, alpha 9 / Q9UGM1* / cholinergic receptor nicotinic alpha 9 subunit* / cholinergic receptor, nicotinic, alpha polypeptide 9*ENSDARG0000005468024
CR847523.1ENSDARG0000010811824
chrna10a / cholinergic receptor, nicotinic, alpha 10aENSDARG0000001111323
LO018568.1 / CHRNA9* / Q9UGM1* / cholinergic receptor nicotinic alpha 9 subunit*ENSDARG0000009918123
htr3a / 5-hydroxytryptamine (serotonin) receptor 3A / P46098* / 5-hydroxytryptamine receptor 3A*ENSDARG0000008921219
htr3b / 5-hydroxytryptamine (serotonin) receptor 3B / O95264* / Q9JHJ5* / 5-hydroxytryptamine receptor 3B*ENSDARG0000006174917
si:ch211-256e16.4ENSDARG0000007842816
FO818743.1ENSDARG0000010267516
si:ch211-256e16.6ENSDARG0000007960314
HTR3C / 5-hydroxytryptamine receptor 3C / HTR3D* / HTR3E* / A5X5Y0* / Q8WXA8* / Q70Z44* / 5-hydroxytryptamine receptor 3D* / 5-hydroxytryptamine receptor 3E*ENSDARG0000007795913
si:dkey-49c17.4ENSDARG0000007482411
si:ch211-256e16.10ENSDARG0000009756610


Protein motifs (from Interpro)
Interpro ID Name
 IPR002394  Nicotinic acetylcholine receptor
 IPR006029  Neurotransmitter-gated ion-channel transmembrane domain
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007271 synaptic transmission, cholinergic IDA
 biological_processGO:0007274 neuromuscular synaptic transmission IBA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035094 response to nicotine IBA
 biological_processGO:0060078 regulation of postsynaptic membrane potential IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 biological_processGO:0098655 cation transmembrane transport IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005892 acetylcholine-gated channel complex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0015464 acetylcholine receptor activity IDA
 molecular_functionGO:0022848 acetylcholine-gated cation-selective channel activity IBA
 molecular_functionGO:0042166 acetylcholine binding IBA


Pathways (from Reactome)
Pathway description
Highly sodium permeable acetylcholine nicotinic receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000101677 chrnb4 / cholinergic receptor, nicotinic, beta 4 (neuronal) / P30926* / Q8R493* / cholinergic receptor nicotinic beta 4 subunit* / cholinergic receptor, nicotinic, beta polypeptide 4*  / complex






 

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