ENSDARG00000034493


Danio rerio

Features
Gene ID: ENSDARG00000034493
  
Biological name :grin2aa
  
Synonyms : glutamate receptor, ionotropic, N-methyl D-aspartate 2A, a / grin2aa
  
Possible biological names infered from orthology : glutamate ionotropic receptor NMDA type subunit 2A / Glutamate receptor ionotropic, NMDA 2A / GRIN2A / P35436 / Q12879
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 27071749
Gene end: 27277695
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000116766
NCBI entrez gene - 563297     See in Manteia.
RefSeq - XM_021473854
swissprot - F6P6I2
ZFIN ID - ZDB-GENE-070424-129
Ensembl - ENSDARG00000034493
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRIN2AENSGALG00000007278Gallus gallus
 GRIN2AENSG00000183454Homo sapiens
 Grin2aENSMUSG00000059003Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
grin2ab / glutamate receptor, ionotropic, N-methyl D-aspartate 2A, b / Q12879* / GRIN2A* / P35436* / Glutamate receptor ionotropic, NMDA 2A * / glutamate ionotropic receptor NMDA type subunit 2A*ENSDARG0000007054362
grin2bb / glutamate receptor, ionotropic, N-methyl D-aspartate 2B, genome duplicate b / GRIN2B* / Q13224* / glutamate receptor, ionotropic, NMDA2B (epsilon 2)* / glutamate ionotropic recept...ENSDARG0000003037652
LO018552.1 / GRIN2B* / Q13224* / glutamate ionotropic receptor NMDA type subunit 2B*ENSDARG0000007934845
grin2ca / glutamate receptor, ionotropic, N-methyl D-aspartate 2Ca / Q14957* / GRIN2C* / Q01098* / Glutamate receptor ionotropic, NMDA 2C * / glutamate ionotropic receptor NMDA type subunit 2C*ENSDARG0000007814939
grin2cb / glutamate receptor, ionotropic, N-methyl D-aspartate 2Cb / Q14957* / GRIN2C* / Q01098* / Glutamate receptor ionotropic, NMDA 2C * / glutamate ionotropic receptor NMDA type subunit 2C*ENSDARG0000007756038
grin2da / glutamate receptor, ionotropic, N-methyl D-aspartate 2D, a / Q03391* / GRIN2D* / O15399* / Glutamate receptor ionotropic, NMDA 2D * / glutamate ionotropic receptor NMDA type subunit 2D*ENSDARG0000008620734
grin2db / glutamate receptor, ionotropic, N-methyl D-aspartate 2D, b / Q03391* / GRIN2D* / O15399* / Glutamate receptor ionotropic, NMDA 2D * / glutamate ionotropic receptor NMDA type subunit 2D*ENSDARG0000007062030
grin3ba / glutamate receptor, ionotropic, N-methyl-D-aspartate 3Ba / Q91ZU9* / GRIN3B* / O60391* / Glutamate receptor ionotropic, NMDA 3B * / glutamate ionotropic receptor NMDA type subunit 3B*ENSDARG0000000536416
grin3a / glutamate receptor, ionotropic, N-methyl-D-aspartate 3A / Q8TCU5* / glutamate ionotropic receptor NMDA type subunit 3A*ENSDARG0000007580216
grin1b / glutamate receptor, ionotropic, N-methyl D-aspartate 1b / GRIN1* / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 * / glutamate ionotropic receptor NMDA type subunit 1*ENSDARG0000002572815
grin1a / glutamate receptor, ionotropic, N-methyl D-aspartate 1a / GRIN1* / P35438* / Q05586* / Glutamate receptor ionotropic, NMDA 1 * / glutamate ionotropic receptor NMDA type subunit 1*ENSDARG0000002782815
grin3bb / glutamate receptor, ionotropic, N-methyl-D-aspartate 3Bb / Q91ZU9* / GRIN3B* / O60391* / Glutamate receptor ionotropic, NMDA 3B * / glutamate ionotropic receptor NMDA type subunit 3B*ENSDARG0000009866715
grik5 / glutamate receptor, ionotropic, kainate 5 / Q16478* / Q61626* / glutamate ionotropic receptor kainate type subunit 5*ENSDARG0000010144914
gria1a / glutamate receptor, ionotropic, AMPA 1a / GRIA1* / P23818* / P42261* / Glutamate receptor 1 * / glutamate ionotropic receptor AMPA type subunit 1*ENSDARG0000002135213
grik4 / glutamate receptor, ionotropic, kainate 4 / Q16099* / Q8BMF5* / glutamate ionotropic receptor kainate type subunit 4*ENSDARG0000002675313
gria1b / glutamate receptor, ionotropic, AMPA 1b / GRIA1* / P23818* / P42261* / Glutamate receptor 1 * / glutamate ionotropic receptor AMPA type subunit 1*ENSDARG0000003271413
grid2 / glutamate receptor, ionotropic, delta 2 / O43424* / Q61625* / glutamate ionotropic receptor delta type subunit 2*ENSDARG0000005530213
gria4b / glutamate receptor, ionotropic, AMPA 4bENSDARG0000005936813
grik1a / glutamate receptor, ionotropic, kainate 1a / GRIK1* / P39086* / glutamate ionotropic receptor kainate type subunit 1* / Mus musculus glutamate receptor, ionotropic, kainate 1 (Grik...ENSDARG0000006913913
GRIK3 / glutamate ionotropic receptor kainate type subunit 3 / Q13003*ENSDARG0000007771513


Protein motifs (from Interpro)
Interpro ID Name
 IPR001320  Ionotropic glutamate receptor
 IPR001508  Ionotropic glutamate receptor, metazoa
 IPR001828  Receptor, ligand binding region
 IPR018884  Glutamate [NMDA] receptor, epsilon subunit, C-terminal
 IPR019594  Ionotropic glutamate receptor, L-glutamate and glycine-binding domain
 IPR028082  Periplasmic binding protein-like I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway IEA
 biological_processGO:0060079 excitatory postsynaptic potential IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0004970 ionotropic glutamate receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005234 extracellularly glutamate-gated ion channel activity IEA


Pathways (from Reactome)
Pathway description
Unblocking of NMDA receptor, glutamate binding and activation
CREB phosphorylation through the activation of CaMKII
Ras activation upon Ca2+ influx through NMDA receptor
RAF/MAP kinase cascade
Synaptic adhesion-like molecules


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr