ENSDARG00000034588


Danio rerio

Features
Gene ID: ENSDARG00000034588
  
Biological name :scn4ab
  
Synonyms : scn4ab / sodium channel, voltage-gated, type IV, alpha, b
  
Possible biological names infered from orthology : P35499 / SCN4A / sodium channel, voltage-gated, type IV, alpha / sodium voltage-gated channel alpha subunit 4
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 22242269
Gene end: 22316844
  
Corresponding Affymetrix probe sets: Dr.26006.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000044156
Ensembl peptide - ENSDARP00000140995
Ensembl peptide - ENSDARP00000094779
NCBI entrez gene - 564977     See in Manteia.
swissprot - E9QB13
swissprot - A0A2C9F1K3
swissprot - A0A0R4IX17
ZFIN ID - ZDB-GENE-051201-1
Ensembl - ENSDARG00000034588
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SCN4AENSGALG00000034427Gallus gallus
 SCN4AENSG00000007314Homo sapiens
 Scn4aENSMUSG00000001027Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
scn4aa / sodium channel, voltage-gated, type IV, alpha, a / SCN4A* / P35499* / sodium voltage-gated channel alpha subunit 4* / sodium channel, voltage-gated, type IV, alpha*ENSDARG0000009873868
scn8ab / sodium channel, voltage gated, type VIII, alpha subunit b / SCN8A* / Q9UQD0* / sodium voltage-gated channel alpha subunit 8* / sodium channel, voltage-gated, type VIII, alpha*ENSDARG0000001803264
scn1lab / sodium channel, voltage-gated, type I like, alpha b / SCN1A* / SCN9A* / SCN7A* / SCN2A* / SCN3A* / A2APX8* / P35498* / Q01118* / Q15858* / Q62205* / Q99250* / Q9NY46* / sodium vol...ENSDARG0000006274464
scn8aa / sodium channel, voltage gated, type VIII, alpha subunit a / SCN8A* / Q9UQD0* / sodium voltage-gated channel alpha subunit 8* / sodium channel, voltage-gated, type VIII, alpha*ENSDARG0000000577563
scn12aa / sodium channel, voltage gated, type XII, alpha a / SCN5A* / Q9R053* / Q9UI33* / Q9Y5Y9* / SCN10A* / SCN11A* / Q14524* / Q6QIY3* / Q9JJV9* / Sodium channel protein type 5 subunit a...ENSDARG0000009072461
scn12ab / sodium channel, voltage gated, type XII, alpha b / SCN5A* / Q9R053* / Q9UI33* / Q9Y5Y9* / SCN10A* / SCN11A* / Q14524* / Q6QIY3* / Q9JJV9* / Sodium channel protein type 5 subunit a...ENSDARG0000010231261
scn1a / sodium channel, voltage-gated, type I, alpha / SCN9A* / SCN3A* / SCN2A* / SCN7A* / A2APX8* / P35498* / Q01118* / Q15858* / Q62205* / Q99250* / Q9NY46* / sodium voltage-gated channel...ENSDARG0000008681958
cacna1ha / calcium channel, voltage-dependent, T type, alpha 1H subunit a / O95180* / CACNA1H* / calcium voltage-gated channel subunit alpha1 H* / voltage-dependent T-type calcium channel s...ENSDARG0000006049623
cacna1i / calcium channel, voltage-dependent, T type, alpha 1I subunit / Q9P0X4* / calcium voltage-gated channel subunit alpha1 I* / calcium channel, voltage-dependent, alpha 1I subunit*ENSDARG0000007052222
cacna1g / calcium channel, voltage-dependent, T type, alpha 1G subunit / O43497* / calcium voltage-gated channel subunit alpha1 G*ENSDARG0000008991322
cacna1hb / calcium channel, voltage-dependent, T type, alpha 1H subunit b / O95180* / CACNA1H* / calcium voltage-gated channel subunit alpha1 H* / voltage-dependent T-type calcium channel s...ENSDARG0000009970819
si:ch73-379f7.5 / CACNA1I (1 of many) / Q9P0X4* / CACNA1I* / calcium voltage-gated channel subunit alpha1 I* / calcium channel, voltage-dependent, alpha 1I subunit*ENSDARG0000009630711
LO017974.1 / Q9P0X4* / CACNA1I* / calcium voltage-gated channel subunit alpha1 I*ENSDARG000001157415


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001696  Voltage gated sodium channel, alpha subunit
 IPR005821  Ion transport domain
 IPR010526  Sodium ion transport-associated
 IPR028817  Voltage gated sodium channel type 4, subunit alpha B


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0001518 voltage-gated sodium channel complex IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005248 voltage-gated sodium channel activity IEA
 molecular_functionGO:0005272 sodium channel activity IEA


Pathways (from Reactome)
Pathway description
Phase 0 - rapid depolarisation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001058 caudal fin caudal fin bent , abnormal
Show

 ZFA:0001094 whole organism whole organism morphology , abnormal
whole organism decreased length , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0005277 skeletal muscle skeletal muscle disorganized , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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