ENSDARG00000035256


Danio rerio

Features
Gene ID: ENSDARG00000035256
  
Biological name :eef2l2
  
Synonyms : eef2l2 / eukaryotic translation elongation factor 2, like 2
  
Possible biological names infered from orthology : EEF2 / Elongation factor 2 / eukaryotic translation elongation factor 2 / P13639 / P58252
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 41485277
Gene end: 41494831
  
Corresponding Affymetrix probe sets: Dr.17513.1.S1_at (Zebrafish Array)   Dr.17513.2.A1_x_at (Zebrafish Array)   Dr.25596.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000051080
NCBI entrez gene - 336168     See in Manteia.
RefSeq - XM_021476571
RefSeq - XM_692874
swissprot - A2CE51
ZFIN ID - ZDB-GENE-030131-8112
Ensembl - ENSDARG00000035256
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 EEF2ENSGALG00000033884Gallus gallus
 EEF2ENSG00000167658Homo sapiens
 Eef2ENSMUSG00000034994Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
eef2b / eukaryotic translation elongation factor 2bENSDARG0000010037193
eef2a.1 / eukaryotic translation elongation factor 2a, tandem duplicate 1ENSDARG0000004209479
eef2a.2 / eukaryotic translation elongation factor 2a, tandem duplicate 2ENSDARG0000004206577


Protein motifs (from Interpro)
Interpro ID Name
 IPR000640  Elongation factor EFG, domain V-like
 IPR000795  Transcription factor, GTP-binding domain
 IPR004161  Translation elongation factor EFTu-like, domain 2
 IPR005225  Small GTP-binding protein domain
 IPR005517  Translation elongation factor EFG/EF2, domain IV
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR014721  Ribosomal protein S5 domain 2-type fold, subgroup
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031157  Tr-type G domain, conserved site
 IPR035647  EF-G domain III/V-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Peptide chain elongation
Synthesis of diphthamide-EEF2
Neutrophil degranulation
Protein methylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000078077 dph2 / A4QN59 / DPH2 homolog (S. cerevisiae) / Q9CR25* / Q9BQC3* / DPH2 homolog* / 2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 *  / reaction
 ENSDARG00000042839 dph6 / A2RV01 / diphthamine biosynthesis 6 / Q7L8W6* / Q9CQ28* / Mus musculus diphthamine biosynthesis 6 (Dph6), transcript variant 3, mRNA.*  / reaction
 ENSDARG00000100242 dph5 / diphthamide biosynthesis 5 / Q9CWQ0* / Q9H2P9* / Diphthine methyl ester synthase *  / reaction






 

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