ENSDARG00000036036


Danio rerio

Features
Gene ID: ENSDARG00000036036
  
Biological name :mdka
  
Synonyms : mdka / midkine a
  
Possible biological names infered from orthology : MDK / midkine / P12025 / P21741
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 39166460
Gene end: 39178198
  
Corresponding Affymetrix probe sets: Dr.20373.1.S2_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000052317
Ensembl peptide - ENSDARP00000142922
Ensembl peptide - ENSDARP00000142902
Ensembl peptide - ENSDARP00000142650
Ensembl peptide - ENSDARP00000117120
NCBI entrez gene - 30277     See in Manteia.
swissprot - E9QIK2
swissprot - A0A1D5NSV1
swissprot - A0A1D5NST4
swissprot - A0A1D5NS41
swissprot - Q9W767
ZFIN ID - ZDB-GENE-990621-1
Ensembl - ENSDARG00000036036
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MDKENSGALG00000008367Gallus gallus
 MDKENSG00000110492Homo sapiens
 MdkENSMUSG00000027239Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mdkb / midkine b / MDK* / P21741* / P12025* / midkine*ENSDARG0000002070862
ptn / pleiotrophin / P21246* / P63089*ENSDARG0000010234040


Protein motifs (from Interpro)
Interpro ID Name
 IPR000762  Midkine heparin-binding growth factor
 IPR020089  Pleiotrophin/Midkine, N-terminal domain
 IPR020090  Pleiotrophin/Midkine, C-terminal domain
 IPR020091  Pleiotrophin/Midkine disulphide-rich domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001841 neural tube formation IMP
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0051726 regulation of cell cycle IMP
 biological_processGO:0070654 sensory epithelium regeneration IMP
 cellular_componentGO:0005794 Golgi apparatus IDA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
NOTCH2 Activation and Transmission of Signal to the Nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000046 retinal neural layer retinal neural layer sensory epithelium regeneration decreased occurrence , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000143 retinal photoreceptor layer retinal photoreceptor layer has fewer parts of type retinal rod cell , abnormal
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 ZFA:0000152 retina retina mitotic cell cycle decreased occurrence , abnormal
retina cell decreased amount , abnormal
retina neuron differentiation delayed , abnormal
retina cell proliferation increased occurrence , abnormal
retina cell cycle process increased duration , abnormal
retina S phase increased duration , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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