response to chemical establishment of localization response to chemical establishment of localization response to chemical establishment of localization response to chemical establishment of localization response to chemical establishment of localization response to chemical establishment of localization response to chemical establishment of localization response to chemical establishment of localization response to chemical establishment of localization response to chemical establishment of localization response to chemicalresponse to chemical establishment of localizationestablishment of localization organic cyclic compound binding heterocyclic compound binding cofactor binding small molecule binding drug binding organic cyclic compound binding heterocyclic compound binding cofactor binding small molecule binding drug binding organic cyclic compound binding heterocyclic compound binding cofactor binding small molecule binding drug binding organic cyclic compound binding heterocyclic compound binding cofactor binding small molecule binding drug binding organic cyclic compound binding heterocyclic compound binding cofactor binding small molecule binding drug binding organic cyclic compound binding heterocyclic compound binding cofactor binding small molecule binding drug binding organic cyclic compound binding heterocyclic compound binding cofactor binding small molecule binding drug binding organic cyclic compound binding heterocyclic compound binding cofactor binding small molecule binding drug binding organic cyclic compound binding heterocyclic compound binding cofactor binding small molecule binding drug binding organic cyclic compound binding heterocyclic compound binding cofactor binding small molecule binding drug binding organic cyclic compound bindorganic cyclic compound binding heterocyclic compound bindinheterocyclic compound binding cofactor bindingcofactor binding small molecule bindingsmall molecule binding drug bindingdrug binding 
