ENSDARG00000037109


Danio rerio

Features
Gene ID: ENSDARG00000037109
  
Biological name :pwp2h
  
Synonyms : pwp2h / PWP2 periodic tryptophan protein homolog (yeast)
  
Possible biological names infered from orthology : FP565260.1 / PWP2 / PWP2, small subunit processome component / Q15269 / Q8BU03
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 28898945
Gene end: 28950366
  
Corresponding Affymetrix probe sets: Dr.3590.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000101591
swissprot - F1RAC4
ZFIN ID - ZDB-GENE-021031-3
Ensembl - ENSDARG00000037109
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000045726Gallus gallus
 FP565260.1ENSG00000275464Homo sapiens
 PWP2ENSG00000241945Homo sapiens
 Pwp2ENSMUSG00000032834Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR007148  Small-subunit processome, Utp12
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR027145  Periodic tryptophan protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000028 ribosomal small subunit assembly IMP
 biological_processGO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0042254 ribosome biogenesis IMP
 biological_processGO:0055123 digestive system development IMP
 cellular_componentGO:0032040 small-subunit processome IBA
 cellular_componentGO:0034388 Pwp2p-containing subcomplex of 90S preribosome IBA
 molecular_functionGO:0030515 snoRNA binding IBA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000076 swim bladder swim bladder uninflated , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000123 liver liver decreased size , abnormal
Show

 ZFA:0000140 pancreas pancreas decreased size , abnormal
Show

 ZFA:0001076 intestinal bulb intestinal bulb decreased size , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
Show

 ZFA:0001114 head head malformed , abnormal
Show

 ZFA:0001338 intestine intestine epithelial cell cuboid , abnormal
Show

 ZFA:0005124 intestinal epithelium intestinal epithelium shape , abnormal
intestinal epithelium decreased thickness , abnormal
intestinal epithelium decreased size , abnormal
intestinal epithelium autophagosome increased amount , abnormal
intestinal epithelium autolysosome increased amount , abnormal
Show

 ZFA:0005125 intestinal villus intestinal villus sparse , abnormal
Show

 ZFA:0005126 intestinal bulb epithelium intestinal bulb epithelium apical-basal axis relative to substrate decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr