ENSDARG00000037963


Danio rerio

Features
Gene ID: ENSDARG00000037963
  
Biological name :nek6
  
Synonyms : nek6 / NIMA-related kinase 6
  
Possible biological names infered from orthology : Q9ES70 / Q9HC98 / Serine/threonine-protein kinase Nek6
  
Species: Danio rerio
  
Chr. number: 21
Strand: -1
Band:
Gene start: 8357602
Gene end: 8370500
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000055327
Ensembl peptide - ENSDARP00000122706
swissprot - F1QT51
swissprot - F1R0M7
ZFIN ID - ZDB-GENE-040724-133
Ensembl - ENSDARG00000037963
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000003979Gallus gallus
 NEK6ENSGALG00000001118Gallus gallus
 NEK6ENSG00000119408Homo sapiens
 Nek6ENSMUSG00000026749Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nek7 / NIMA-related kinase 7 / Q8TDX7* / Q9ES74* / Serine/threonine-protein kinase Nek7 *ENSDARG0000005696680
nek2 / NIMA-related kinase 2 / O35942* / P51955* / Serine/threonine-protein kinase Nek2 *ENSDARG0000000561936
NEK3 / NIMA related kinase 3 / P51956*ENSDARG0000005886933
nek4 / NIMA-related kinase 4 / P51957*ENSDARG0000004015232
nek8 / NIMA-related kinase 8 / Q86SG6* / Q91ZR4* / Serine/threonine-protein kinase Nek8 *ENSDARG0000004562632
nek12 / NIMA-related kinase 12 / NEK9* / Q8TD19* / Q8K1R7* / NIMA related kinase 9* / Serine/threonine-protein kinase Nek9 *ENSDARG0000003717430
nek11 / NIMA-related kinase 11 / Q8C0Q4* / Q8NG66* / Serine/threonine-protein kinase Nek11 *ENSDARG0000008756428
nek1 / NIMA-related kinase 1 / P51954* / Q96PY6* / NIMA (never in mitosis gene a)-related expressed kinase 1*ENSDARG0000002235010


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Activation of NIMA Kinases NEK9, NEK6, NEK7
Nuclear Pore Complex (NPC) Disassembly


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000037174 nek12 / NIMA-related kinase 12 / NEK9* / Q8TD19* / Q8K1R7* / NIMA related kinase 9* / Serine/threonine-protein kinase Nek9 *  / complex / reaction






 

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