ENSDARG00000038500


Danio rerio

Features
Gene ID: ENSDARG00000038500
  
Biological name :cep41
  
Synonyms : centrosomal protein 41 / cep41 / Q6GQN0
  
Possible biological names infered from orthology : Centrosomal protein of 41 kDa / Q99NF3 / Q9BYV8
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 18436301
Gene end: 18445279
  
Corresponding Affymetrix probe sets: Dr.18520.1.S1_at (Zebrafish Array)   NM_001002194_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000056179
NCBI entrez gene - 431741     See in Manteia.
RefSeq - NM_001002194
RefSeq Peptide - NP_001002194
swissprot - Q6GQN0
ZFIN ID - ZDB-GENE-040704-35
Ensembl - ENSDARG00000038500
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CEP41ENSGALG00000008103Gallus gallus
 CEP41ENSG00000106477Homo sapiens
 Cep41ENSMUSG00000029790Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001763  Rhodanese-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0018095 protein polyglutamylation IMP
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0035082 axoneme assembly IMP
 biological_processGO:0060271 cilium assembly IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005814 centriole ISS
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005929 cilium ISS
 cellular_componentGO:0036064 ciliary basal body ISS
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0070740 tubulin-glutamic acid ligase activity IMP


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle cilium non-functional , abnormal
Show

 ZFA:0000008 brain brain hydrocephalic , abnormal
Show

 ZFA:0000114 heart heart edematous , abnormal
heart inverted , abnormal
Show

 ZFA:0000150 pronephric duct pronephric duct axonemal microtubule increased amount , abnormal
pronephric duct axonemal microtubule decreased size , abnormal
pronephric duct axoneme morphology , abnormal
Show

 ZFA:0000217 inner ear inner ear altered number of otolith , abnormal
Show

 ZFA:0001117 post-vent region post-vent region morphology , abnormal
post-vent region curved , abnormal
Show

 ZFA:0001617 otolith otolith position , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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