ENSDARG00000038743


Danio rerio

Features
Gene ID: ENSDARG00000038743
  
Biological name :copb2
  
Synonyms : coatomer protein complex, subunit beta 2 / copb2
  
Possible biological names infered from orthology : Coatomer subunit beta / O55029 / P35606
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 38997357
Gene end: 39015130
  
Corresponding Affymetrix probe sets: Dr.14625.1.A1_at (Zebrafish Array)   Dr.14625.1.A1_s_at (Zebrafish Array)   Dr.14687.1.A1_at (Zebrafish Array)   NM_001001940_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000044330
NCBI entrez gene - 114454     See in Manteia.
RefSeq - NM_001001940
RefSeq Peptide - NP_001001940
swissprot - B0R171
ZFIN ID - ZDB-GENE-010724-7
Ensembl - ENSDARG00000038743
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 COPB2ENSGALG00000005357Gallus gallus
 COPB2ENSG00000184432Homo sapiens
 Copb2ENSMUSG00000032458Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR006692  Coatomer, WD associated region
 IPR011044  Quinoprotein amine dehydrogenase, beta chain-like
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016453  Coatomer beta" subunit (COPB2)
 IPR017986  WD40-repeat-containing domain
 IPR020472  G-protein beta WD-40 repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006886 intracellular protein transport IBA
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IBA
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER IBA
 biological_processGO:0006891 intra-Golgi vesicle-mediated transport IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030903 notochord development IMP
 biological_processGO:0061053 somite development IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030117 membrane coat IEA
 cellular_componentGO:0030126 COPI vesicle coat IBA
 cellular_componentGO:0030663 COPI-coated vesicle membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0005198 structural molecule activity IEA


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000135 notochord notochord quality , abnormal
notochord structure , abnormal
notochord poorly differentiated , abnormal
notochord undifferentiated , abnormal
notochord decreased length , abnormal
notochord apoptotic , abnormal
notochord basement membrane decreased thickness , abnormal
notochord basement membrane disorganized , abnormal
notochord basal lamina absent , abnormal
notochord endoplasmic reticulum swollen , abnormal
notochord Golgi apparatus structure , abnormal
notochord cell structure , abnormal
Show

 ZFA:0000155 somite somite size , abnormal
somite condensed , abnormal
somite morphology , abnormal
Show

 ZFA:0001094 whole organism whole organism lethal (sensu genetics) , abnormal
whole organism degenerate , abnormal
whole organism shape , abnormal
whole organism decreased length , abnormal
whole organism viability , abnormal
Show

 ZFA:0001115 trunk trunk melanosome absent , abnormal
Show

 ZFA:0009091 melanocyte melanocyte melanosome absent , abnormal
Show

 ZFA:0009114 muscle cell muscle cell endoplasmic reticulum swollen , abnormal
muscle cell Golgi apparatus structure , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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