ENSDARG00000040163


Danio rerio

Features
Gene ID: ENSDARG00000040163
  
Biological name :prim1
  
Synonyms : DNA primase subunit 1 / prim1
  
Possible biological names infered from orthology : DNA primase, p49 subunit / P20664 / P49642
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 17839187
Gene end: 17848907
  
Corresponding Affymetrix probe sets: Dr.377.1.S1_at (Zebrafish Array)   NM_201448_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000095418
NCBI entrez gene - 30440     See in Manteia.
RefSeq - NM_201448
RefSeq Peptide - NP_958856
swissprot - F1QKT6
ZFIN ID - ZDB-GENE-990603-6
Ensembl - ENSDARG00000040163
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRIM1ENSGALG00000041973Gallus gallus
 PRIM1ENSG00000198056Homo sapiens
 Prim1ENSMUSG00000025395Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002755  DNA primase, small subunit
 IPR014052  DNA primase, small subunit, eukaryotic/archaeal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006269 DNA replication, synthesis of RNA primer IBA
 cellular_componentGO:0005658 alpha DNA polymerase:primase complex IBA
 molecular_functionGO:0003697 single-stranded DNA binding IBA
 molecular_functionGO:0003896 DNA primase activity IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Inhibition of replication initiation of damaged DNA by RB1/E2F1
Polymerase switching on the C-strand of the telomere
Telomere C-strand synthesis initiation
DNA replication initiation
Activation of the pre-replicative complex
Polymerase switching
Removal of the Flap Intermediate
Processive synthesis on the lagging strand


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000046 retinal neural layer retinal neural layer apoptotic process occurrence , ameliorated
retinal neural layer apoptotic process increased occurrence , abnormal
Show

 ZFA:0000107 eye eye morphology , ameliorated
eye morphology , abnormal
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 ZFA:0000152 retina retina apoptotic , abnormal
retina central region apoptotic , abnormal
retina apoptotic process occurrence , ameliorated
retina morphology , abnormal
retina cell death increased occurrence , abnormal
retina structure , ameliorated
retina apoptotic process increased occurrence , abnormal
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 ZFA:0000445 optic tectum optic tectum cell death increased occurrence , abnormal
Show

 ZFA:0001458 cranial cartilage cranial cartilage morphology , abnormal
Show

 ZFA:0009262 retinal cone cell retinal cone cell amount , ameliorated
retinal cone cell absent , abnormal
Show

 ZFA:0009310 retinal ganglion cell retinal ganglion cell amount , ameliorated
retinal ganglion cell absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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