ENSDARG00000040623


Danio rerio

Features
Gene ID: ENSDARG00000040623
  
Biological name :fosl2
  
Synonyms : fosl2 / fos-like antigen 2
  
Possible biological names infered from orthology : FOS like 2, AP-1 transcription factor subunit / Fos-related antigen 2 / P15408 / P47930
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 41302660
Gene end: 41318547
  
Corresponding Affymetrix probe sets: Dr.10130.1.S1_at (Zebrafish Array)   Dr.10130.2.A1_at (Zebrafish Array)   Dr.10410.1.A1_at (Zebrafish Array)   NM_001082998_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000059479
NCBI entrez gene - 558921     See in Manteia.
RefSeq - NM_001082998
RefSeq Peptide - NP_001076467
swissprot - A2RUX8
ZFIN ID - ZDB-GENE-070209-164
Ensembl - ENSDARG00000040623
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FOSL2ENSGALG00000010036Gallus gallus
 FOSL2ENSG00000075426Homo sapiens
 Fosl2ENSMUSG00000029135Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
fosb / FBJ murine osteosarcoma viral oncogene homolog B / P13346* / P53539* / Protein fosB * / FosB proto-oncogene, AP-1 transcription factor subunit*ENSDARG0000005575140
fosl1a / FOS-like antigen 1a / FOSL1* / P15407* / P48755* / Fos-related antigen 1 * / FOS like 1, AP-1 transcription factor subunit*ENSDARG0000001535537
fosab / v-fos FBJ murine osteosarcoma viral oncogene homolog Ab / FOS* / P01100* / P01101* / Proto-onco c-Fos * / Fos proto-oncogene, AP-1 transcription factor subunit*ENSDARG0000003168337
fosaa / v-fos FBJ murine osteosarcoma viral oncogene homolog AaENSDARG0000004013533
si:ch211-153j24.3ENSDARG0000006842826
si:ch211-59d15.4ENSDARG0000009217419
fosl1b / FOS-like antigen 1bENSDARG0000007937316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000837  AP-1 transcription factor
 IPR004827  Basic-leucine zipper domain
 IPR029814  Fos-related antigen 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:2000690 regulation of cardiac muscle cell myoblast differentiation IMP
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000009 cardiac ventricle cardiac ventricle cardiac muscle cell decreased amount , abnormal
cardiac ventricle cardiac muscle tissue growth increased rate , abnormal
cardiac ventricle cardiac muscle tissue growth decreased rate , abnormal
cardiac ventricle cardiac muscle tissue growth hypotrophic growth , abnormal
cardiac ventricle decreased size , abnormal
Show

 ZFA:0000037 anatomical structure anatomical structure absent , abnormal
anatomical structure decreased amount , abnormal
anatomical structure increased amount , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000114 heart heart increased amount , abnormal
heart increased distribution , abnormal
Show

 ZFA:0000173 bulbus arteriosus bulbus arteriosus muscle precursor cell increased amount , abnormal
bulbus arteriosus smooth muscle absent , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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