ENSDARG00000040955


Danio rerio

Features
Gene ID: ENSDARG00000040955
  
Biological name :dharma
  
Synonyms : dharma
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 29011290
Gene end: 29012493
  
Corresponding Affymetrix probe sets: Dr.619.1.S1_at (Zebrafish Array)   NM_130979_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000060017
NCBI entrez gene - 30170     See in Manteia.
RefSeq - NM_130979
RefSeq Peptide - NP_571054
swissprot - F1R8X3
ZFIN ID - ZDB-GENE-990415-22
Ensembl - ENSDARG00000040955
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000047  Helix-turn-helix motif
 IPR001356  Homeobox domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0003140 determination of left/right asymmetry in lateral mesoderm IMP
 biological_processGO:0003143 embryonic heart tube morphogenesis IMP
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0009880 embryonic pattern specification IMP
 biological_processGO:0014028 notochord formation IMP
 biological_processGO:0030903 notochord development IMP
 biological_processGO:0033504 floor plate development IMP
 biological_processGO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway IGI
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0048319 axial mesoderm morphogenesis IMP
 biological_processGO:0048320 axial mesoderm formation IMP
 biological_processGO:0048592 eye morphogenesis IMP
 biological_processGO:0048854 brain morphogenesis IMP
 biological_processGO:0060061 Spemann organizer formation IMP
 biological_processGO:0061053 somite development IMP
 biological_processGO:2000223 regulation of BMP signaling pathway involved in heart jogging IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle absent , abnormal
Show

 ZFA:0000008 brain brain morphology , abnormal
brain quality , abnormal
Show

 ZFA:0000022 floor plate floor plate absent , abnormal
floor plate quality , abnormal
floor plate decreased size , abnormal
floor plate malformed , abnormal
Show

 ZFA:0000026 hatching gland hatching gland hypoplastic , abnormal
Show

 ZFA:0000032 hypothalamus hypothalamus decreased size , abnormal
Show

 ZFA:0000060 prechordal plate prechordal plate absent , abnormal
prechordal plate hypoplastic , abnormal
Show

 ZFA:0000071 shield shield absent , abnormal
shield blastomere mislocalised , abnormal
Show

 ZFA:0000075 spinal cord spinal cord morphology , abnormal
Show

 ZFA:0000091 axial chorda mesoderm axial chorda mesoderm aplastic , abnormal
axial chorda mesoderm hypoplastic , abnormal
Show

 ZFA:0000101 diencephalon diencephalon ventral region hypoplastic , abnormal
Show

 ZFA:0000107 eye eye fused with eye , abnormal
eye decreased size , abnormal
eye absent , abnormal
eye quality , abnormal
Show

 ZFA:0000109 forebrain forebrain absent , abnormal
Show

 ZFA:0000114 heart heart quality , abnormal
Show

 ZFA:0000128 midbrain midbrain ventral region hypoplastic , abnormal
Show

 ZFA:0000131 neural keel neural keel hypoplastic , abnormal
neural keel morphology , abnormal
Show

 ZFA:0000135 notochord notochord absent , abnormal
notochord quality , abnormal
notochord malformed , abnormal
notochord aplastic , abnormal
notochord structure , abnormal
notochord hypoplastic , abnormal
notochord poorly differentiated , abnormal
notochord broken , abnormal
notochord morphology , abnormal
Show

 ZFA:0000152 retina retina apoptotic , abnormal
retina stratification , abnormal
Show

 ZFA:0000155 somite somite fused with somite , abnormal
somite shape , abnormal
somite quality , abnormal
Show

 ZFA:0000282 sensory system sensory system quality , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0000671 horizontal myoseptum horizontal myoseptum hypoplastic , abnormal
Show

 ZFA:0000890 floor plate spinal cord region floor plate spinal cord region ventral-most region hypoplastic , abnormal
Show

 ZFA:0001094 whole organism whole organism wholly ventralized , abnormal
whole organism decreased size , abnormal
whole organism lethal (sensu genetics) , abnormal
Show

 ZFA:0001114 head head morphology , abnormal
Show

 ZFA:0001115 trunk trunk notochord aplastic , abnormal
trunk has fewer parts of type notochord cell, abnormal
Show

 ZFA:0001120 neuroectoderm neuroectoderm morphology , abnormal
neuroectoderm anterior region truncated , abnormal
Show

 ZFA:0001204 axial mesoderm axial mesoderm absent , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0009091 melanocyte melanocyte displaced to neural tube ventral surface, abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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