ENSDARG00000041113


Danio rerio

Features
Gene ID: ENSDARG00000041113
  
Biological name :wdr18
  
Synonyms : Q68EI0 / wdr18 / WD repeat domain 18
  
Possible biological names infered from orthology : Q4VBE8 / Q9BV38
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 13642157
Gene end: 13789451
  
Corresponding Affymetrix probe sets: Dr.809.1.A1_at (Zebrafish Array)   NM_001005206_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000060250
NCBI entrez gene - 445819     See in Manteia.
RefSeq - NM_001005206
RefSeq Peptide - NP_001005206
swissprot - B2GT94
swissprot - Q68EI0
ZFIN ID - ZDB-GENE-040905-4
Ensembl - ENSDARG00000041113
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 WDR18ENSGALG00000021637Gallus gallus
 WDR18ENSG00000065268Homo sapiens
 Wdr18ENSMUSG00000035754Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011047  Quinoprotein alcohol dehydrogenase-like superfamily
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR026987  WD repeat-containing protein 18, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007368 determination of left/right symmetry IGI
 biological_processGO:0070121 Kupffer"s vesicle development IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000001 Kupffer s vesicle Kupffers vesicle decreased size , abnormal
Kupffers vesicle decreased functionality , abnormal
Kupffers vesicle bicellular tight junction disorganized , abnormal
Kupffers vesicle cilium decreased length , abnormal
Kupffers vesicle cilium decreased amount , abnormal
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 ZFA:0000023 forerunner cell group forerunner cell group mislocalised , abnormal
Show

 ZFA:0000140 pancreas pancreas mislocalised , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000079313 pelp1 / proline, glutamate and leucine rich protein 1 / Q8IZL8* / Q9DBD5* / Proline-, glutamic acid- and leucine-rich protein 1 *  / complex






 

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