ENSDARG00000041449


Danio rerio

Features
Gene ID: ENSDARG00000041449
  
Biological name :spred1
  
Synonyms : spred1 / sprouty-related, EVH1 domain containing 1
  
Possible biological names infered from orthology : Q7Z699 / Q924S8 / Sprouty-related, EVH1 domain-containing protein 1
  
Species: Danio rerio
  
Chr. number: 17
Strand: -1
Band:
Gene start: 52639492
Gene end: 52659119
  
Corresponding Affymetrix probe sets: Dr.10038.1.S1_at (Zebrafish Array)   Dr.23460.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000060763
Ensembl peptide - ENSDARP00000147699
swissprot - F1R8L9
ZFIN ID - ZDB-GENE-040426-2338
Ensembl - ENSDARG00000041449
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPRED1ENSGALG00000028203Gallus gallus
 Q7Z699ENSG00000166068Homo sapiens
 Q924S8ENSMUSG00000027351Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
spred2b / sprouty-related, EVH1 domain containing 2b / Q924S7* / SPRED2* / Q7Z698* / sprouty related EVH1 domain containing 2* / Sprouty-related, EVH1 domain-containing protein 2 *ENSDARG0000000837252
spred2a / sprouty-related, EVH1 domain containing 2a / Q924S7* / SPRED2* / Q7Z698* / sprouty related EVH1 domain containing 2* / Sprouty-related, EVH1 domain-containing protein 2 *ENSDARG0000005243550
spred3 / sprouty-related, EVH1 domain containing 3 / Q2MJR0*ENSDARG0000004035841
enah / enabled homolog (Drosophila) / Q03173* / Q8N8S7* / ENAH, actin regulator*ENSDARG0000003204918
evla / Enah/Vasp-like a / EVL* / Q9UI08* / P70429* / Enah/Vasp-like* / Ena/VASP-like protein *ENSDARG0000003565017
vaspb / vasodilator stimulated phosphoprotein b / VASP* / P50552* / P70460* / vasodilator stimulated phosphoprotein*ENSDARG0000001710516
vaspa / vasodilator stimulated phosphoprotein a / VASP* / P50552* / vasodilator stimulated phosphoprotein*ENSDARG0000009969016
evlb / Enah/Vasp-like bENSDARG0000009972015


Protein motifs (from Interpro)
Interpro ID Name
 IPR000697  WH1/EVH1 domain
 IPR007875  Sprouty
 IPR011993  PH-like domain superfamily
 IPR023337  c-Kit-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway IMP
 biological_processGO:0048514 blood vessel morphogenesis IMP
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs
FGFRL1 modulation of FGFR1 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart edematous , abnormal
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 ZFA:0001267 cranial vasculature cranial vasculature broken , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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