ENSDARG00000042824


Danio rerio

Features
Gene ID: ENSDARG00000042824
  
Biological name :nfe2l2a
  
Synonyms : nfe2l2a / nuclear factor, erythroid 2-like 2a
  
Possible biological names infered from orthology : NFE2L2 / nuclear factor, erythroid 2 like 2 / Nuclear factor erythroid 2-related factor 2 / Q16236 / Q60795
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 1654284
Gene end: 1683368
  
Corresponding Affymetrix probe sets: Dr.12684.1.S1_at (Zebrafish Array)   Dr.12684.1.S2_at (Zebrafish Array)   Dr.7230.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000062853
NCBI entrez gene - 360149     See in Manteia.
RefSeq - XM_005172511
swissprot - Q7ZVI2
ZFIN ID - ZDB-GENE-030723-2
Ensembl - ENSDARG00000042824
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NFE2L2ENSGALG00000009240Gallus gallus
 NFE2L2ENSG00000116044Homo sapiens
 Nfe2l2ENSMUSG00000015839Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nfe2l2b / nuclear factor, erythroid 2-like 2bENSDARG0000008969723
nfe2 / nuclear factor, erythroid 2 / Q16621*ENSDARG0000002060621
nfe2l1a / nuclear factor, erythroid 2-like 1a / NFE2L1* / Q14494* / Q61985* / nuclear factor, erythroid 2 like 1* / Nuclear factor erythroid 2-related factor 1 *ENSDARG0000003061621
nfe2l3 / nuclear factor, erythroid 2-like 3 / Q9Y4A8*ENSDARG0000001981016
bach2b / BTB and CNC homology 1, basic leucine zipper transcription factor 2b / BACH2* / P97303* / Q9BYV9* / BTB domain and CNC homolog 2* / Transcription regulator protein BACH2 *ENSDARG0000000407414
bach2a / BTB and CNC homology 1, basic leucine zipper transcription factor 2a / BACH2* / P97303* / Q9BYV9* / BTB domain and CNC homolog 2* / Transcription regulator protein BACH2 *ENSDARG0000003656914
bach1b / BTB and CNC homology 1, basic leucine zipper transcription factor 1 b / BACH1* / O14867* / BTB domain and CNC homolog 1*ENSDARG0000000219612
bach1a / BTB and CNC homology 1, basic leucine zipper transcription factor 1 a / BACH1* / O14867* / P97302* / BTB domain and CNC homolog 1* / Transcription regulator protein BACH1 *ENSDARG0000006255312


Protein motifs (from Interpro)
Interpro ID Name
 IPR004826  Basic leucine zipper domain, Maf-type
 IPR004827  Basic-leucine zipper domain
 IPR008917  Transcription factor, Skn-1-like, DNA-binding domain superfamily
 IPR029845  Nuclear factor erythroid 2-related factor 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IMP
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006979 response to oxidative stress IMP
 biological_processGO:0034599 cellular response to oxidative stress IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IGI
 biological_processGO:0071379 cellular response to prostaglandin stimulus IMP
 biological_processGO:0071466 cellular response to xenobiotic stimulus IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000976 transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IPI
 molecular_functionGO:0003700 DNA-binding transcription factor activity IGI
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure glutathione disulfide increased amount , abnormal
anatomical structure glutathione decreased amount , abnormal
anatomical structure amount , ameliorated
anatomical structure increased amount , abnormal
Show

 ZFA:0000123 liver liver amount , ameliorated
liver increased amount , abnormal
Show

 ZFA:0000354 gill gill increased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism amount , ameliorated
whole organism decreased life span , abnormal
whole organism dead , abnormal
whole organism increased amount , abnormal
Show

 ZFA:0001338 intestine intestine increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr