ENSDARG00000042845


Danio rerio
hormoneoxtneurohypophysialactivityhomeostasisgalphasignallingeventsclathrin-mediatedendocytosisionocyteconservedsiteregulationsignalingreceptorionextracellularregionneurohypophysealvasopressin-likereceptorsqsvasopressinregulatesrenalwaterviaaquaporins

Features
Gene ID: ENSDARG00000042845
  
Biological name :oxt
  
Synonyms : oxt / oxytocin
  
Possible biological names infered from orthology : arginine vasopressin / AVP / oxytocin/neurophysin I prepropeptide / P01178 / P01185 / P35454 / P35455
  
Species: Danio rerio
  
Chr. number: 5
Strand: 1
Band:
Gene start: 72087619
Gene end: 72093253
  
Corresponding Affymetrix probe sets: Dr.7597.1.S1_at (Zebrafish Array)   NM_178291_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000062884
NCBI entrez gene - 352920     See in Manteia.
RefSeq - NM_178291
RefSeq Peptide - NP_840076
swissprot - F1QC27
ZFIN ID - ZDB-GENE-030407-1
Ensembl - ENSDARG00000042845
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000019026Gallus gallus
 AVPENSGALG00000014117Gallus gallus
 AVPENSG00000101200Homo sapiens
 OXTENSG00000101405Homo sapiens
 AvpENSMUSG00000037727Mus musculus
 OxtENSMUSG00000027301Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
avp / arginine vasopressin / OXT* / P35455* / P01185* / P35454* / P01178* / oxytocin* / oxytocin/neurophysin I prepropeptide*ENSDARG0000005856752


Protein motifs (from Interpro)
Interpro ID Name
 IPR000981  Neurohypophysial hormone
 IPR022423  Neurohypophysial hormone, conserved site


Gene Ontology (GO)
cell communicationregulation of molecular functioncellular response to stimulusregulation of biological qualitycell communicationregulation of molecular functioncellular response to stimulusregulation of biological qualitycell communicationregulation of molecular functioncellular response to stimulusregulation of biological qualitycell communicationregulation of molecular functioncellular response to stimulusregulation of biological qualitycell communicationregulation of molecular functioncellular response to stimulusregulation of biological qualitycell communicationregulation of molecular functioncellular response to stimulusregulation of biological qualitycell communicationregulation of molecular functioncellular response to stimulusregulation of biological qualitycell communicationregulation of molecular functioncellular response to stimulusregulation of biological qualitycell communicationregulation of molecular functioncellular response to stimulusregulation of biological qualitycell communicationregulation of molecular functioncellular response to stimulusregulation of biological qualitycell communicationcell communicationregulation of molecular functionregulation of molecular functioncellular response to stimuluscellular response to stimulusregulation of biological qualityregulation of biological quality
protein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingprotein bindingreceptor regulator activityreceptor regulator activity
extracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular regionextracellular region
TypeGO IDTermEv.Code
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0050801 ion homeostasis IMP
 cellular_componentGO:0005576 extracellular region IEA
 molecular_functionGO:0005185 neurohypophyseal hormone activity IEA


Pathways (from Reactome)
Pathway description
Vasopressin-like receptors
G alpha (q) signalling events
G alpha (s) signalling events
Vasopressin regulates renal water homeostasis via Aquaporins
Transport of organic anions
Cargo recognition for clathrin-mediated endocytosis
Clathrin-mediated endocytosis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000105 epidermis epidermis somatic stem cell decreased amount , abnormal
Show

 ZFA:0001271 neurohypophysis neurohypophysis vasculature malformed , abnormal
Show

 ZFA:0005326 NaK ionocyte NaK ionocyte decreased amount , abnormal
Show

 ZFA:0005327 vH ionocyte vH ionocyte decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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