ENSDARG00000044575


Danio rerio

Features
Gene ID: ENSDARG00000044575
  
Biological name :vars
  
Synonyms : valyl-tRNA synthetase / vars
  
Possible biological names infered from orthology : P26640 / Q9Z1Q9
  
Species: Danio rerio
  
Chr. number: 16
Strand: 1
Band:
Gene start: 10429770
Gene end: 10475814
  
Corresponding Affymetrix probe sets: Dr.1481.1.A1_at (Zebrafish Array)   Dr.1481.2.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000142328
NCBI entrez gene - 114427     See in Manteia.
RefSeq - NM_001311346
RefSeq Peptide - NP_001298275
swissprot - F1Q740
ZFIN ID - ZDB-GENE-010601-1
Ensembl - ENSDARG00000044575
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 VARSENSG00000204394Homo sapiens
 VarsENSMUSG00000007029Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
vars2 / valyl-tRNA synthetase 2, mitochondrial (putative) / Q3U2A8* / Q5ST30* / valyl-tRNA synthetase 2, mitochondrial*ENSDARG0000005671738


Protein motifs (from Interpro)
Interpro ID Name
 IPR001412  Aminoacyl-tRNA synthetase, class I, conserved site
 IPR002300  Aminoacyl-tRNA synthetase, class Ia
 IPR002303  Valine-tRNA ligase
 IPR004046  Glutathione S-transferase, C-terminal
 IPR009008  Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain
 IPR009080  Aminoacyl-tRNA synthetase, class Ia, anticodon-binding
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR013155  Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding
 IPR014729  Rossmann-like alpha/beta/alpha sandwich fold
 IPR019499  Valyl-tRNA synthetase, tRNA-binding arm
 IPR033705  Valyl tRNA synthetase, anticodon-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation IEA
 biological_processGO:0006418 tRNA aminoacylation for protein translation IEA
 biological_processGO:0006438 valyl-tRNA aminoacylation IEA
 biological_processGO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0002161 aminoacyl-tRNA editing activity IEA
 molecular_functionGO:0004812 aminoacyl-tRNA ligase activity IEA
 molecular_functionGO:0004832 valine-tRNA ligase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016874 ligase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk grey , abnormal
yolk swollen , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000112 gut gut hypoplastic , abnormal
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 ZFA:0000114 heart heart quality , abnormal
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 ZFA:0000123 liver liver hypoplastic , abnormal
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 ZFA:0001114 head head decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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