ENSDARG00000044902


Danio rerio

Features
Gene ID: ENSDARG00000044902
  
Biological name :atp2b2
  
Synonyms : atp2b2 / atp2b4 / ATPase plasma membrane Ca2+ transporting 2
  
Possible biological names infered from orthology : ATPase plasma membrane Ca2+ transporting 4 / P23634 / Plasma membrane calcium-transporting ATPase 4 / Q6Q477
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 22920587
Gene end: 23080970
  
Corresponding Affymetrix probe sets: Dr.16761.1.A1_at (Zebrafish Array)   Dr.17051.1.A1_at (Zebrafish Array)   Dr.17051.1.A1_a_at (Zebrafish Array)   Dr.6752.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000147194
Ensembl peptide - ENSDARP00000153564
Ensembl peptide - ENSDARP00000046121
Ensembl peptide - ENSDARP00000109303
Ensembl peptide - ENSDARP00000130984
Ensembl peptide - ENSDARP00000136538
swissprot - A0A0R4IAQ9
swissprot - A0A0R4IKR3
swissprot - F1QKF2
swissprot - F1R790
ZFIN ID - ZDB-GENE-061016-1
ZFIN ID - ZDB-GENE-061027-60
Ensembl - ENSDARG00000044902
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATP2B4ENSGALG00000003601Gallus gallus
 ATP2B4ENSG00000058668Homo sapiens
 Atp2b4ENSMUSG00000026463Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
atp2b1a / ATPase plasma membrane Ca2+ transporting 1a / ATP2B1* / G5E829* / P20020* / ATPase plasma membrane Ca2+ transporting 1* / Plasma membrane calcium-transporting ATPase 1 *ENSDARG0000001268477
atp2b2 / ATPase plasma membrane Ca2+ transporting 2 / Q01814*ENSDARG0000006343377
atp2b1b / ATPase plasma membrane Ca2+ transporting 1b / ATP2B1* / G5E829* / P20020* / ATPase plasma membrane Ca2+ transporting 1* / Plasma membrane calcium-transporting ATPase 1 *ENSDARG0000000778875
atp2b3b / ATPase plasma membrane Ca2+ transporting 3b / Q16720* / ATP2B3* / ATPase plasma membrane Ca2+ transporting 3* / ATPase, Ca++ transporting, plasma membrane 3*ENSDARG0000002344574
atp2b3a / ATPase plasma membrane Ca2+ transporting 3a / Q16720* / ATP2B3* / ATPase plasma membrane Ca2+ transporting 3* / ATPase, Ca++ transporting, plasma membrane 3*ENSDARG0000004347474


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR004014  Cation-transporting P-type ATPase, N-terminal
 IPR006068  Cation-transporting P-type ATPase, C-terminal
 IPR006408  P-type ATPase, subfamily IIB
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR022141  Plasma membrane calcium transporting P-type ATPase, C-terminal
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N
 IPR034304  Plasma membrane calcium-transporting ATPase 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IBA
 biological_processGO:0070588 calcium ion transmembrane transport IEA
 biological_processGO:0099132 ATP hydrolysis coupled cation transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005388 calcium-transporting ATPase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030165 PDZ domain binding IBA


Pathways (from Reactome)
Pathway description
Reduction of cytosolic Ca++ levels
Ion homeostasis
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000068910 nos1 / nitric oxide synthase 1 (neuronal) / Q9Z0J4* / P29475* / nitric oxide synthase 1* / Nitric oxide synthase, brain *  / complex / reaction






 

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