ENSDARG00000045131


Danio rerio

Features
Gene ID: ENSDARG00000045131
  
Biological name :id4
  
Synonyms : id4 / inhibitor of DNA binding 4
  
Possible biological names infered from orthology : DNA-binding protein inhibitor ID-4 / inhibitor of DNA binding 4, HLH protein / P41139 / P47928
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 9977858
Gene end: 9980402
  
Corresponding Affymetrix probe sets: Dr.2993.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000066371
NCBI entrez gene - 664761     See in Manteia.
RefSeq - NM_001039990
RefSeq Peptide - NP_001035079
swissprot - Q32PN8
ZFIN ID - ZDB-GENE-051113-208
Ensembl - ENSDARG00000045131
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ID4ENSGALG00000039474Gallus gallus
 ID4ENSG00000172201Homo sapiens
 Id4ENSMUSG00000021379Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
id2a / inhibitor of DNA binding 2a / ID2* / P41136* / Q02363* / inhibitor of DNA binding 2* / DNA-binding protein inhibitor ID-2 *ENSDARG0000005528344
id1 / inhibitor of DNA binding 1 / P20067* / P41134* / inhibitor of DNA binding 1, HLH protein*ENSDARG0000004076440
id3 / inhibitor of DNA binding 3 / P41133* / Q02535* / DNA-binding protein inhibitor ID-3 * / inhibitor of DNA binding 3, HLH protein*ENSDARG0000005482338
id2b / inhibitor of DNA binding 2b / ID2* / P41136* / Q02363* / inhibitor of DNA binding 2* / DNA-binding protein inhibitor ID-2 *ENSDARG0000002954436


Protein motifs (from Interpro)
Interpro ID Name
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain
 IPR026052  DNA-binding protein inhibitor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003171 atrioventricular valve development IMP
 biological_processGO:0003307 regulation of Wnt signaling pathway involved in heart development IMP
 biological_processGO:0036302 atrioventricular canal development IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain amount , ameliorated
Show

 ZFA:0000009 cardiac ventricle cardiac ventricle mislocalised , abnormal
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 ZFA:0000114 heart heart amount , ameliorated
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 ZFA:0000154 sinus venosus sinus venosus mislocalised , abnormal
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 ZFA:0000471 atrium atrium mislocalised , abnormal
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 ZFA:0001317 endocardial cushion endocardial cushion increased distribution , abnormal
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 ZFA:0001616 atrioventricular canal endocardium atrioventricular canal endocardium decreased amount , abnormal
atrioventricular canal endocardium cell increased distribution , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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