ENSDARG00000045680


Danio rerio
proteinnucleusnucleartnpo3armadillo-likehelicalexportin-importin-beta-likearmadillo-typefoldmrnaprocessingimportrnasplicingtcelldifferentiationcytoplasmmembranelocalizationsequencebindingtransporteractivitythymus

Features
Gene ID: ENSDARG00000045680
  
Biological name :tnpo3
  
Synonyms : tnpo3 / transportin 3
  
Possible biological names infered from orthology : Mus musculus transportin 3 (Tnpo3), transcript variant 2, mRNA. / Q6P2B1 / Q9Y5L0
  
Species: Danio rerio
  
Chr. number: 4
Strand: 1
Band:
Gene start: 13586455
Gene end: 13605158
  
Corresponding Affymetrix probe sets: Dr.2195.1.S1_at (Zebrafish Array)   NM_201087_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000067160
Ensembl peptide - ENSDARP00000120894
Ensembl peptide - ENSDARP00000156422
NCBI entrez gene - 394062     See in Manteia.
RefSeq - NM_201087
RefSeq Peptide - NP_957381
swissprot - Q5RHV1
swissprot - Q7ZW13
ZFIN ID - ZDB-GENE-040426-708
Ensembl - ENSDARG00000045680
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TNPO3ENSGALG00000039420Gallus gallus
 TNPO3ENSG00000064419Homo sapiens
 Tnpo3ENSMUSG00000012535Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:ch73-182a11.2ENSDARG0000007699623
ipo13 / importin 13 / O94829*ENSDARG0000006061822


Protein motifs (from Interpro)
Interpro ID Name
 IPR011989  Armadillo-like helical
 IPR013598  Exportin-1/Importin-beta-like
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
nitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processcell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processcell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processcell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processcell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processcell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processcell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processcell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processcell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processcell activationnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationestablishment of localizationcellular localizationanatomical structure developmentcellular developmental processcell activationnitrogen componitrogen compound metabolic processcellular metabcellular metabolic processprimary metaboprimary metabolic processorganic substaorganic substance metabolic processmacromolecule macromolecule localizationestablishment establishment of localizationcellular localcellular localizationanatomical stranatomical structure developmentcellular develcellular developmental processcell activatiocell activation
amide bindingprotein transporter activityamide bindingprotein transporter activityamide bindingprotein transporter activityamide bindingprotein transporter activityamide bindingprotein transporter activityamide bindingprotein transporter activityamide bindingprotein transporter activityamide bindingprotein transporter activityamide bindingprotein transporter activityamide bindingprotein transporter activityamide bindingamide bindingprotein transporter activityprotein transporter activity
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0006397 mRNA processing IMP
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0008380 RNA splicing IMP
 biological_processGO:0030217 T cell differentiation IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0031965 nuclear membrane IBA
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0008565 protein transporter activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001078 thymus thymus decreased amount , abnormal
thymus T cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr