ENSDARG00000052594


Danio rerio

Features
Gene ID: ENSDARG00000052594
  
Biological name :nkiras2
  
Synonyms : NFKB inhibitor interacting Ras-like 2 / nkiras2
  
Possible biological names infered from orthology : NF-kappa-B inhibitor-interacting Ras-like protein 2 / Q9CR56 / Q9NYR9
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 17867126
Gene end: 17871860
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000068967
Ensembl peptide - ENSDARP00000154067
NCBI entrez gene - 445039     See in Manteia.
RefSeq - NM_001003433
RefSeq Peptide - NP_001003433
swissprot - F1QJH0
ZFIN ID - ZDB-GENE-040801-166
Ensembl - ENSDARG00000052594
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q5ZJW6ENSGALG00000028971Gallus gallus
 Q9NYR9ENSG00000168256Homo sapiens
 Q9CR56ENSMUSG00000017837Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6DGQ1 / nkiras1 / NFKB inhibitor interacting Ras-like 1 / Q8CEC5* / Q9NYS0* / NF-kappa-B inhibitor-interacting Ras-like protein 1 *ENSDARG0000009952766


Protein motifs (from Interpro)
Interpro ID Name
 IPR001806  Small GTPase superfamily
 IPR005225  Small GTP-binding protein domain
 IPR020849  Small GTPase superfamily, Ras-type
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003924 GTPase activity IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
RIP-mediated NFkB activation via ZBP1
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
TRAF6 mediated NF-kB activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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