ENSDARG00000054799


Danio rerio

Features
Gene ID: ENSDARG00000054799
  
Biological name :rfc1
  
Synonyms : replication factor C (activator 1) 1 / rfc1 / rpl9
  
Possible biological names infered from orthology : P35251 / replication factor C subunit 1
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 23243093
Gene end: 23274038
  
Corresponding Affymetrix probe sets: Dr.1202.3.S1_at (Zebrafish Array)   Dr.17100.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000113369
Ensembl peptide - ENSDARP00000119715
Ensembl peptide - ENSDARP00000156035
NCBI entrez gene - 100037336     See in Manteia.
NCBI entrez gene - 336702     See in Manteia.
RefSeq - NM_001089491
RefSeq Peptide - NP_001082960
swissprot - E9QDP5
swissprot - F1Q5P6
ZFIN ID - ZDB-GENE-030131-8646
ZFIN ID - ZDB-GENE-070410-99
Ensembl - ENSDARG00000054799
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RFC1ENSGALG00000014298Gallus gallus
 RFC1ENSG00000035928Homo sapiens
 Rfc1ENSMUSG00000029191Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000702  Ribosomal protein L6
 IPR001357  BRCT domain
 IPR002359  Ribosomal protein L6, conserved site-2
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR008921  DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
 IPR012178  Replication factor C subunit 1
 IPR013725  DNA replication factor RFC1, C-terminal
 IPR020040  Ribosomal protein L6, alpha-beta domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005663 DNA replication factor C complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0003689 DNA clamp loader activity IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Polymerase switching on the C-strand of the telomere
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Homologous Recombination (HRR)
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Polymerase switching


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000042 midbrain hindbrain boundary midbrain hindbrain boundary condensed , abnormal
midbrain hindbrain boundary quality , abnormal
Show

 ZFA:0000076 swim bladder swim bladder quality , abnormal
Show

 ZFA:0000084 yolk yolk circular , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000112 gut gut hypoplastic , abnormal
gut quality , abnormal
Show

 ZFA:0000123 liver liver hypoplastic , abnormal
liver quality , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr