ENSDARG00000055470


Danio rerio

Features
Gene ID: ENSDARG00000055470
  
Biological name :cdc16
  
Synonyms : cdc16 / cell division cycle 16 homolog (S. cerevisiae)
  
Possible biological names infered from orthology : Cell division cycle / cell division cycle 16 / Q13042 / Q8R349
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 34920001
Gene end: 34937256
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000072280
Ensembl peptide - ENSDARP00000117611
NCBI entrez gene - 562014     See in Manteia.
RefSeq - NM_001037389
RefSeq Peptide - NP_001032466
swissprot - B0V222
swissprot - B0S729
ZFIN ID - ZDB-GENE-051113-132
Ensembl - ENSDARG00000055470
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CDC16ENSGALG00000016816Gallus gallus
 CDC16ENSG00000130177Homo sapiens
 Cdc16ENSMUSG00000038416Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IMP


Pathways (from Reactome)
Pathway description
Inactivation of APC/C via direct inhibition of the APC/C complex
APC/C:Cdc20 mediated degradation of Cyclin B
Autodegradation of Cdh1 by Cdh1:APC/C
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
Regulation of APC/C activators between G1/S and early anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Phosphorylation of the APC/C
APC-Cdc20 mediated degradation of Nek2A
Separation of Sister Chromatids
Senescence-Associated Secretory Phenotype (SASP)
CDK-mediated phosphorylation and removal of Cdc6
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000107 eye eye decreased size , abnormal
eye apoptotic , abnormal
Show

 ZFA:0000108 fin fin morphology , abnormal
Show

 ZFA:0000554 olfactory epithelium olfactory epithelium morphology , abnormal
Show

 ZFA:0001094 whole organism whole organism apoptotic , abnormal
Show

 ZFA:0001249 exocrine pancreas exocrine pancreas decreased length , abnormal
exocrine pancreas degenerate , abnormal
exocrine pancreas retracted , abnormal
Show

 ZFA:0001289 ciliary marginal zone ciliary marginal zone decreased size , abnormal
ciliary marginal zone spindle orientation retinal pigmented epithelium , abnormal
ciliary marginal zone spindle structure , abnormal
ciliary marginal zone spindle increased amount , abnormal
ciliary marginal zone spindle apical-basal polarity , abnormal
Show

 ZFA:0001518 ceratobranchial 3 cartilage ceratobranchial 3 cartilage decreased length , abnormal
Show

 ZFA:0001519 ceratobranchial 4 cartilage ceratobranchial 4 cartilage decreased length , abnormal
Show

 ZFA:0001521 ceratobranchial 5 cartilage ceratobranchial 5 cartilage decreased length , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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